http://purl.uniprot.org/citations/15796965 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/15796965 | http://www.w3.org/2000/01/rdf-schema#comment | "Malignant rhabdoid tumors (MRT) of the liver are rare. A few liver MRT cell lines have been established but none has been characterized in detail. Here we describe a new MRT cell line from the liver, which is designated MP-MRT-AN, and describe it in detail. Immunohistochemical assays detected the expression of vimentin and cytokeratin but they were negative for neurofilament, desmin, alpha-smooth muscle actin, alpha-sarcomeric actin, and smooth muscle myosin heavy chains SM1 and SM2. RT-PCR assays revealed that this cell line did not express smooth muscle myosin heavy chain isoforms or MyoD1. No aberration was identified in 22q by G-banded analysis; however, the hSNF5/INI1 gene, a suppressor gene of MRT that maps to 22q11.2, was homozygously deleted from exons 1 to 5 in this cell line. Furthermore, the expression of another tumor suppressor gene, p16 (CDKN2A), was not detected by RT-PCR. This raises the possibility that the aggressive phenotype of malignant rhabdoid tumors is caused by the loss of two or more tumor suppressor genes."xsd:string |
http://purl.uniprot.org/citations/15796965 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.cancergencyto.2004.08.032"xsd:string |
http://purl.uniprot.org/citations/15796965 | http://purl.uniprot.org/core/author | "Kuroda H."xsd:string |
http://purl.uniprot.org/citations/15796965 | http://purl.uniprot.org/core/author | "Inazawa J."xsd:string |
http://purl.uniprot.org/citations/15796965 | http://purl.uniprot.org/core/author | "Sawada K."xsd:string |
http://purl.uniprot.org/citations/15796965 | http://purl.uniprot.org/core/author | "Sugimoto T."xsd:string |
http://purl.uniprot.org/citations/15796965 | http://purl.uniprot.org/core/author | "Imoto I."xsd:string |
http://purl.uniprot.org/citations/15796965 | http://purl.uniprot.org/core/author | "Kuwahara Y."xsd:string |
http://purl.uniprot.org/citations/15796965 | http://purl.uniprot.org/core/author | "Moritake H."xsd:string |
http://purl.uniprot.org/citations/15796965 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
http://purl.uniprot.org/citations/15796965 | http://purl.uniprot.org/core/name | "Cancer Genet Cytogenet"xsd:string |
http://purl.uniprot.org/citations/15796965 | http://purl.uniprot.org/core/pages | "172-179"xsd:string |
http://purl.uniprot.org/citations/15796965 | http://purl.uniprot.org/core/title | "Establishment of a cell line from a malignant rhabdoid tumor of the liver lacking the function of two tumor suppressor genes, hSNF5/INI1 and p16."xsd:string |
http://purl.uniprot.org/citations/15796965 | http://purl.uniprot.org/core/volume | "158"xsd:string |
http://purl.uniprot.org/citations/15796965 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/15796965 |
http://purl.uniprot.org/citations/15796965 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/15796965 |
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http://purl.uniprot.org/uniprot/#_B4E117-mappedCitation-15796965 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15796965 |
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http://purl.uniprot.org/uniprot/#_Q12824-mappedCitation-15796965 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15796965 |
http://purl.uniprot.org/uniprot/#_Q6Q321-mappedCitation-15796965 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15796965 |
http://purl.uniprot.org/uniprot/#_Q86WI6-mappedCitation-15796965 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15796965 |
http://purl.uniprot.org/uniprot/#_Q86WI7-mappedCitation-15796965 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15796965 |
http://purl.uniprot.org/uniprot/#_Q86WI8-mappedCitation-15796965 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15796965 |