http://purl.uniprot.org/citations/15797730 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/15797730 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/15797730 | http://www.w3.org/2000/01/rdf-schema#comment | "The Dugesia japonica vasa-like gene B (DjVLGB) protein is a DEAD-box RNA helicase of a planarian, which is well known for its strong regenerative capacity. DjVLGB shares sequence similarity to the Drosophila germ-line-specific DEAD-box RNA helicase Vasa, and even higher similarity to its paralogue, mouse PL10. In this study, we solved the crystal structure of the DjVLGB N-terminal RecA-like domain. The overall fold and the structures of the putative ATPase active site of the DjVLGB N-terminal RecA-like domain are similar to those of the previously reported DEAD-box RNA helicase structures. In contrast, the surface structure of the side opposite to the putative ATPase active site is different from those of the other DEAD-box RNA helicases; the characteristic hydrophobic pockets are formed with aromatic and proline residues. These pocket-forming residues are conserved in the PL10-subfamily proteins, but less conserved in the Vasa orthologues and not conserved in the DEAD-box RNA helicases. Therefore, the structural features that we found are characteristic of the PL10-subfamily proteins and might contribute to their biological roles in germ-line development."xsd:string |
http://purl.uniprot.org/citations/15797730 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.jsb.2005.01.006"xsd:string |
http://purl.uniprot.org/citations/15797730 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.jsb.2005.01.006"xsd:string |
http://purl.uniprot.org/citations/15797730 | http://purl.uniprot.org/core/author | "Aoki M."xsd:string |
http://purl.uniprot.org/citations/15797730 | http://purl.uniprot.org/core/author | "Aoki M."xsd:string |
http://purl.uniprot.org/citations/15797730 | http://purl.uniprot.org/core/author | "Okumura H."xsd:string |
http://purl.uniprot.org/citations/15797730 | http://purl.uniprot.org/core/author | "Okumura H."xsd:string |
http://purl.uniprot.org/citations/15797730 | http://purl.uniprot.org/core/author | "Shirouzu M."xsd:string |
http://purl.uniprot.org/citations/15797730 | http://purl.uniprot.org/core/author | "Shirouzu M."xsd:string |
http://purl.uniprot.org/citations/15797730 | http://purl.uniprot.org/core/author | "Terada T."xsd:string |
http://purl.uniprot.org/citations/15797730 | http://purl.uniprot.org/core/author | "Terada T."xsd:string |
http://purl.uniprot.org/citations/15797730 | http://purl.uniprot.org/core/author | "Tanaka A."xsd:string |
http://purl.uniprot.org/citations/15797730 | http://purl.uniprot.org/core/author | "Tanaka A."xsd:string |
http://purl.uniprot.org/citations/15797730 | http://purl.uniprot.org/core/author | "Yokoyama S."xsd:string |
http://purl.uniprot.org/citations/15797730 | http://purl.uniprot.org/core/author | "Yokoyama S."xsd:string |
http://purl.uniprot.org/citations/15797730 | http://purl.uniprot.org/core/author | "Kigawa T."xsd:string |
http://purl.uniprot.org/citations/15797730 | http://purl.uniprot.org/core/author | "Kigawa T."xsd:string |
http://purl.uniprot.org/citations/15797730 | http://purl.uniprot.org/core/author | "Shibata N."xsd:string |
http://purl.uniprot.org/citations/15797730 | http://purl.uniprot.org/core/author | "Shibata N."xsd:string |
http://purl.uniprot.org/citations/15797730 | http://purl.uniprot.org/core/author | "Yabuki T."xsd:string |
http://purl.uniprot.org/citations/15797730 | http://purl.uniprot.org/core/author | "Yabuki T."xsd:string |
http://purl.uniprot.org/citations/15797730 | http://purl.uniprot.org/core/author | "Matsuda T."xsd:string |
http://purl.uniprot.org/citations/15797730 | http://purl.uniprot.org/core/author | "Matsuda T."xsd:string |