| http://purl.uniprot.org/citations/15799966 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15799966 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15799966 | http://www.w3.org/2000/01/rdf-schema#comment | "MURR1 is a multifunctional protein that inhibits nuclear factor kappaB (NF-kappaB), a transcription factor with pleiotropic functions affecting innate and adaptive immunity, apoptosis, cell cycle regulation, and oncogenesis. Here we report the discovery of a new family of proteins with homology to MURR1. These proteins form multimeric complexes and were identified in a biochemical screen for MURR1-associated factors. The family is defined by the presence of a conserved and unique motif termed the COMM (copper metabolism gene MURR1) domain, which functions as an interface for protein-protein interactions. Like MURR1, several of these factors also associate with and inhibit NF-kappaB. The proteins designated as COMMD or COMM domain containing 1-10 are extensively conserved in multicellular eukaryotic organisms and define a novel family of structural and functional homologs of MURR1. The prototype of this family, MURR1/COMMD1, suppresses NF-kappaB not by affecting nuclear translocation or binding of NF-kappaB to cognate motifs; rather, it functions in the nucleus by affecting the association of NF-kappaB with chromatin."xsd:string |
| http://purl.uniprot.org/citations/15799966 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.m501928200"xsd:string |
| http://purl.uniprot.org/citations/15799966 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.m501928200"xsd:string |
| http://purl.uniprot.org/citations/15799966 | http://purl.uniprot.org/core/author | "Csomos R.A."xsd:string |
| http://purl.uniprot.org/citations/15799966 | http://purl.uniprot.org/core/author | "Csomos R.A."xsd:string |
| http://purl.uniprot.org/citations/15799966 | http://purl.uniprot.org/core/author | "Duckett C.S."xsd:string |
| http://purl.uniprot.org/citations/15799966 | http://purl.uniprot.org/core/author | "Duckett C.S."xsd:string |
| http://purl.uniprot.org/citations/15799966 | http://purl.uniprot.org/core/author | "Wilkinson A.S."xsd:string |
| http://purl.uniprot.org/citations/15799966 | http://purl.uniprot.org/core/author | "Wilkinson A.S."xsd:string |
| http://purl.uniprot.org/citations/15799966 | http://purl.uniprot.org/core/author | "Wilkinson J.C."xsd:string |
| http://purl.uniprot.org/citations/15799966 | http://purl.uniprot.org/core/author | "Wilkinson J.C."xsd:string |
| http://purl.uniprot.org/citations/15799966 | http://purl.uniprot.org/core/author | "Burstein E."xsd:string |
| http://purl.uniprot.org/citations/15799966 | http://purl.uniprot.org/core/author | "Burstein E."xsd:string |
| http://purl.uniprot.org/citations/15799966 | http://purl.uniprot.org/core/author | "Maine G.N."xsd:string |
| http://purl.uniprot.org/citations/15799966 | http://purl.uniprot.org/core/author | "Maine G.N."xsd:string |
| http://purl.uniprot.org/citations/15799966 | http://purl.uniprot.org/core/author | "Mayo M.W."xsd:string |
| http://purl.uniprot.org/citations/15799966 | http://purl.uniprot.org/core/author | "Mayo M.W."xsd:string |
| http://purl.uniprot.org/citations/15799966 | http://purl.uniprot.org/core/author | "Rumble J.M."xsd:string |
| http://purl.uniprot.org/citations/15799966 | http://purl.uniprot.org/core/author | "Rumble J.M."xsd:string |
| http://purl.uniprot.org/citations/15799966 | http://purl.uniprot.org/core/author | "Hoberg J.E."xsd:string |
| http://purl.uniprot.org/citations/15799966 | http://purl.uniprot.org/core/author | "Hoberg J.E."xsd:string |
| http://purl.uniprot.org/citations/15799966 | http://purl.uniprot.org/core/author | "Komarck C.M."xsd:string |
| http://purl.uniprot.org/citations/15799966 | http://purl.uniprot.org/core/author | "Komarck C.M."xsd:string |