http://purl.uniprot.org/citations/15814683 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/15814683 | http://www.w3.org/2000/01/rdf-schema#comment | "Among T cell subsets, gamma delta T cells uniquely display an Ag receptor-based tissue distribution, but what defines their preferential homing and homeostasis is unknown. To address this question, we studied the resources that control gamma delta T cell homeostasis in secondary lymphoid organs. We found that gamma delta and alpha beta T cells are controlled by partially overlapping resources, because acute homeostatic proliferation of gamma delta T cells was inhibited by an intact alpha beta T cell compartment, and both populations were dependent on IL-7 and IL-15. Significantly, to undergo acute homeostatic proliferation, gamma delta T cells also required their own depletion. Thus, gamma delta T cell homeostasis is maintained by trophic cytokines commonly used by other types of lymphoid cells, as well as by additional, as yet unidentified, gamma delta-specific factors."xsd:string |
http://purl.uniprot.org/citations/15814683 | http://purl.org/dc/terms/identifier | "doi:10.4049/jimmunol.174.8.4606"xsd:string |
http://purl.uniprot.org/citations/15814683 | http://purl.uniprot.org/core/author | "Havran W.L."xsd:string |
http://purl.uniprot.org/citations/15814683 | http://purl.uniprot.org/core/author | "Baccala R."xsd:string |
http://purl.uniprot.org/citations/15814683 | http://purl.uniprot.org/core/author | "Gonzalez-Quintial R."xsd:string |
http://purl.uniprot.org/citations/15814683 | http://purl.uniprot.org/core/author | "Theofilopoulos A.N."xsd:string |
http://purl.uniprot.org/citations/15814683 | http://purl.uniprot.org/core/author | "Surh C.D."xsd:string |
http://purl.uniprot.org/citations/15814683 | http://purl.uniprot.org/core/author | "Witherden D."xsd:string |
http://purl.uniprot.org/citations/15814683 | http://purl.uniprot.org/core/author | "Dummer W."xsd:string |
http://purl.uniprot.org/citations/15814683 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
http://purl.uniprot.org/citations/15814683 | http://purl.uniprot.org/core/name | "J Immunol"xsd:string |
http://purl.uniprot.org/citations/15814683 | http://purl.uniprot.org/core/pages | "4606-4612"xsd:string |
http://purl.uniprot.org/citations/15814683 | http://purl.uniprot.org/core/title | "Gamma delta T cell homeostasis is controlled by IL-7 and IL-15 together with subset-specific factors."xsd:string |
http://purl.uniprot.org/citations/15814683 | http://purl.uniprot.org/core/volume | "174"xsd:string |
http://purl.uniprot.org/citations/15814683 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/15814683 |
http://purl.uniprot.org/citations/15814683 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/15814683 |
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