http://purl.uniprot.org/citations/15820312 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/15820312 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/15820312 | http://www.w3.org/2000/01/rdf-schema#comment | "Monosomy 7 and deletions of 7q are recurring leukemia-associated cytogenetic abnormalities that correlate with adverse outcomes in children and adults. We describe a 2.52-Mb genomic DNA contig that spans a commonly deleted segment of chromosome band 7q22 identified in myeloid malignancies. This interval currently includes 14 genes, 19 predicted genes, and 5 predicted pseudogenes. We have extensively characterized the FBXL13, NAPE-PLD, and SVH genes as candidate myeloid tumor suppressors. FBXL13 encodes a novel F-box protein, SVHis a member of a gene family that contains Armadillo-like repeats, and NAPE-PLD encodes a phospholipase D-type phosphodiesterase. Analysis of a panel of leukemia specimens with monosomy 7 did not reveal mutations in these or in the candidate genes LRRC17, PRO1598, and SRPK2. This fully sequenced and annotated contig provides a resource for candidate myeloid tumor suppressor gene discovery."xsd:string |
http://purl.uniprot.org/citations/15820312 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.ygeno.2005.01.013"xsd:string |
http://purl.uniprot.org/citations/15820312 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.ygeno.2005.01.013"xsd:string |
http://purl.uniprot.org/citations/15820312 | http://purl.uniprot.org/core/author | "Green E.D."xsd:string |
http://purl.uniprot.org/citations/15820312 | http://purl.uniprot.org/core/author | "Green E.D."xsd:string |
http://purl.uniprot.org/citations/15820312 | http://purl.uniprot.org/core/author | "Le Beau M.M."xsd:string |
http://purl.uniprot.org/citations/15820312 | http://purl.uniprot.org/core/author | "Le Beau M.M."xsd:string |
http://purl.uniprot.org/citations/15820312 | http://purl.uniprot.org/core/author | "Kratz C.P."xsd:string |
http://purl.uniprot.org/citations/15820312 | http://purl.uniprot.org/core/author | "Kratz C.P."xsd:string |
http://purl.uniprot.org/citations/15820312 | http://purl.uniprot.org/core/author | "Bonifas J.M."xsd:string |
http://purl.uniprot.org/citations/15820312 | http://purl.uniprot.org/core/author | "Bonifas J.M."xsd:string |
http://purl.uniprot.org/citations/15820312 | http://purl.uniprot.org/core/author | "Shannon K.M."xsd:string |
http://purl.uniprot.org/citations/15820312 | http://purl.uniprot.org/core/author | "Shannon K.M."xsd:string |
http://purl.uniprot.org/citations/15820312 | http://purl.uniprot.org/core/author | "Balkman J.D."xsd:string |
http://purl.uniprot.org/citations/15820312 | http://purl.uniprot.org/core/author | "Balkman J.D."xsd:string |
http://purl.uniprot.org/citations/15820312 | http://purl.uniprot.org/core/author | "Curtiss N.P."xsd:string |
http://purl.uniprot.org/citations/15820312 | http://purl.uniprot.org/core/author | "Curtiss N.P."xsd:string |
http://purl.uniprot.org/citations/15820312 | http://purl.uniprot.org/core/author | "Emerling B.M."xsd:string |
http://purl.uniprot.org/citations/15820312 | http://purl.uniprot.org/core/author | "Emerling B.M."xsd:string |
http://purl.uniprot.org/citations/15820312 | http://purl.uniprot.org/core/author | "Lauchle J.O."xsd:string |
http://purl.uniprot.org/citations/15820312 | http://purl.uniprot.org/core/author | "Lauchle J.O."xsd:string |
http://purl.uniprot.org/citations/15820312 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
http://purl.uniprot.org/citations/15820312 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |