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http://purl.uniprot.org/citations/15834408http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/15834408http://www.w3.org/2000/01/rdf-schema#comment"In the developing brain, the organization of the neuroepithelium is maintained by a critical balance between proliferation and cell-cell adhesion of neural progenitor cells. The molecular mechanisms that underlie this are still largely unknown. Here, through analysis of a conditional knockout mouse for the Kap3 gene, we show that post-Golgi transport of N-cadherin by the KIF3 molecular motor complex is crucial for maintaining this balance. N-cadherin and beta-catenin associate with the KIF3 complex by co-immunoprecipitation, and colocalize with KIF3 in cells. Furthermore, in KAP3-deficient cells, the subcellular localization of N-cadherin was disrupted. Taken together, these results suggest a potential tumour-suppressing activity for this molecular motor."xsd:string
http://purl.uniprot.org/citations/15834408http://purl.org/dc/terms/identifier"doi:10.1038/ncb1249"xsd:string
http://purl.uniprot.org/citations/15834408http://purl.uniprot.org/core/author"Hirokawa N."xsd:string
http://purl.uniprot.org/citations/15834408http://purl.uniprot.org/core/author"Nakata T."xsd:string
http://purl.uniprot.org/citations/15834408http://purl.uniprot.org/core/author"Tanaka Y."xsd:string
http://purl.uniprot.org/citations/15834408http://purl.uniprot.org/core/author"Takei Y."xsd:string
http://purl.uniprot.org/citations/15834408http://purl.uniprot.org/core/author"Kulkarni A.B."xsd:string
http://purl.uniprot.org/citations/15834408http://purl.uniprot.org/core/author"Rai T."xsd:string
http://purl.uniprot.org/citations/15834408http://purl.uniprot.org/core/author"Hirasawa M."xsd:string
http://purl.uniprot.org/citations/15834408http://purl.uniprot.org/core/author"Teng J."xsd:string
http://purl.uniprot.org/citations/15834408http://purl.uniprot.org/core/date"2005"xsd:gYear
http://purl.uniprot.org/citations/15834408http://purl.uniprot.org/core/name"Nat Cell Biol"xsd:string
http://purl.uniprot.org/citations/15834408http://purl.uniprot.org/core/pages"474-482"xsd:string
http://purl.uniprot.org/citations/15834408http://purl.uniprot.org/core/title"The KIF3 motor transports N-cadherin and organizes the developing neuroepithelium."xsd:string
http://purl.uniprot.org/citations/15834408http://purl.uniprot.org/core/volume"7"xsd:string
http://purl.uniprot.org/citations/15834408http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/15834408
http://purl.uniprot.org/citations/15834408http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/15834408
http://purl.uniprot.org/uniprot/P70188#attribution-259F22FD10581D0C0978B8010E6814EDhttp://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/15834408
http://purl.uniprot.org/uniprot/#_D3Z7S6-mappedCitation-15834408http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15834408
http://purl.uniprot.org/uniprot/#_E9QAK5-mappedCitation-15834408http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15834408
http://purl.uniprot.org/uniprot/#_A0A1B0GQV9-mappedCitation-15834408http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15834408
http://purl.uniprot.org/uniprot/#_A0A1D5RM76-mappedCitation-15834408http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15834408
http://purl.uniprot.org/uniprot/#_D3YYT0-mappedCitation-15834408http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15834408
http://purl.uniprot.org/uniprot/#_D3Z5Q1-mappedCitation-15834408http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15834408