http://purl.uniprot.org/citations/15856945 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/15856945 | http://www.w3.org/2000/01/rdf-schema#comment | "The allele and genotype frequencies of polymorphic markers of NOS1, NOS2 and NOS3 genes, encoding three types of NO synthases, were compared in type 1 diabetes patients with and without diabetic polyneuropathty. 180 type 1 diabetes patients (T1DM) of Russian or Eastern Slavonic origin, living in Moscow city, were divided into two groups using non-overlapping (polar) phenotypes. 86 patients had overt DPN and T1DM duration in this group was less than 5 years (DPN+ group) and 94 patients had no clinical DPN and T1DM duration was more than 10 years (DPN-group). We have not found the significant differences of allele and genotype frequencies of polymorphic markers (CA)n of NOS1 gene, (CCTTT)n of NOS2 gene, ecNOS4a/4b and Glu298Asp of NOS3 gene that indicates that all these markers are not associated with diabetic polyneuropathty. Only in the case of (CCTTT)n marker of NOS2 gene we have found a tendency for the association of 14 allele with DPN development. The carriers of this allele have the lower risk of DPN in T1DM."xsd:string |
http://purl.uniprot.org/citations/15856945 | http://purl.uniprot.org/core/author | "Nosikov V.V."xsd:string |
http://purl.uniprot.org/citations/15856945 | http://purl.uniprot.org/core/author | "Zotova E.V."xsd:string |
http://purl.uniprot.org/citations/15856945 | http://purl.uniprot.org/core/author | "Bursa T.R."xsd:string |
http://purl.uniprot.org/citations/15856945 | http://purl.uniprot.org/core/author | "Galeev I.V."xsd:string |
http://purl.uniprot.org/citations/15856945 | http://purl.uniprot.org/core/author | "Strokov I.A."xsd:string |
http://purl.uniprot.org/citations/15856945 | http://purl.uniprot.org/core/author | "Voron'ko O.E."xsd:string |
http://purl.uniprot.org/citations/15856945 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
http://purl.uniprot.org/citations/15856945 | http://purl.uniprot.org/core/name | "Mol Biol (Mosk)"xsd:string |
http://purl.uniprot.org/citations/15856945 | http://purl.uniprot.org/core/pages | "224-229"xsd:string |
http://purl.uniprot.org/citations/15856945 | http://purl.uniprot.org/core/title | "[Polymorphic markers of the NO synthase genes and genetic predisposition to diabetic polyneuropathy in patients with type 1 diabetes mellitus]."xsd:string |
http://purl.uniprot.org/citations/15856945 | http://purl.uniprot.org/core/volume | "39"xsd:string |
http://purl.uniprot.org/citations/15856945 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/15856945 |
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