http://purl.uniprot.org/citations/15864309 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/15864309 | http://www.w3.org/2000/01/rdf-schema#comment | "The form in which antigens are transferred from cancer cells or infected cells to antigen-presenting cells as a part of the process of priming CD8(+) T cells has been a longstanding unresolved issue. Intact proteins or protein fragments in the form of free peptides or peptides chaperoned by heat-shock protein are possible sources of antigen. We address this here using beta-galactosidase and ovalbumin. Immunization with cell lysates containing intact proteins and heat-shock protein-peptide complexes or with cell lysates depleted of either component demonstrated that protein fragments chaperoned by heat-shock protein and not intact protein were the necessary and sufficient source of antigen transferred to antigen-presenting cells for priming CD8(+) T cell responses."xsd:string |
http://purl.uniprot.org/citations/15864309 | http://purl.org/dc/terms/identifier | "doi:10.1038/ni1201"xsd:string |
http://purl.uniprot.org/citations/15864309 | http://purl.uniprot.org/core/author | "Srivastava P.K."xsd:string |
http://purl.uniprot.org/citations/15864309 | http://purl.uniprot.org/core/author | "Binder R.J."xsd:string |
http://purl.uniprot.org/citations/15864309 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
http://purl.uniprot.org/citations/15864309 | http://purl.uniprot.org/core/name | "Nat Immunol"xsd:string |
http://purl.uniprot.org/citations/15864309 | http://purl.uniprot.org/core/pages | "593-599"xsd:string |
http://purl.uniprot.org/citations/15864309 | http://purl.uniprot.org/core/title | "Peptides chaperoned by heat-shock proteins are a necessary and sufficient source of antigen in the cross-priming of CD8+ T cells."xsd:string |
http://purl.uniprot.org/citations/15864309 | http://purl.uniprot.org/core/volume | "6"xsd:string |
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