http://purl.uniprot.org/citations/1587794 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/1587794 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/1587794 | http://www.w3.org/2000/01/rdf-schema#comment | "We previously reported that the mouse macrophage galacose and N-acetylgalactosamine-specific lectin (MMGL) may participate in the binding of the macrophages to tumor cells [Oda, S., Sato, M., Toyoshima, S., & Osawa, T. (1989) J. Biochem. 105, 1040-1043]. We now report the cloning and characterization of a cDNA encoding MMGL. The MMGL gene encoded a protein consisting of 304 amino acid residues with a molecular weight of 34,595. The deduced amino acid sequence indicated that MMGL had a single membrane-spanning region, three leucine zipper-like domains, and a carbohydrate recognition domain. Two N-glycosylation sites were found in the extracellular region of MMGL, corresponding to the heavy N-glycosylation in the native MMGL. Comparison of the amino acid sequence of MMGL with those of rat hepatic lectins revealed a high overall sequence homology. The sequence homology was especially high in the putative membrane-spanning region and carbohydrate recognition domain. There was, however, a region of 25 amino acids which did not exist on hepatic lectins. The MMGL cDNA without the region encoding the putative membrane-spanning region and intracellular region was expressed in Escherichia coli. The expressed protein had galactose-binding activity and its sugar-binding specificity was same as that of the native lectin."xsd:string |
http://purl.uniprot.org/citations/1587794 | http://purl.org/dc/terms/identifier | "doi:10.1093/oxfordjournals.jbchem.a123758"xsd:string |
http://purl.uniprot.org/citations/1587794 | http://purl.org/dc/terms/identifier | "doi:10.1093/oxfordjournals.jbchem.a123758"xsd:string |
http://purl.uniprot.org/citations/1587794 | http://purl.uniprot.org/core/author | "Sato M."xsd:string |
http://purl.uniprot.org/citations/1587794 | http://purl.uniprot.org/core/author | "Sato M."xsd:string |
http://purl.uniprot.org/citations/1587794 | http://purl.uniprot.org/core/author | "Osawa T."xsd:string |
http://purl.uniprot.org/citations/1587794 | http://purl.uniprot.org/core/author | "Osawa T."xsd:string |
http://purl.uniprot.org/citations/1587794 | http://purl.uniprot.org/core/author | "Toyoshima S."xsd:string |
http://purl.uniprot.org/citations/1587794 | http://purl.uniprot.org/core/author | "Toyoshima S."xsd:string |
http://purl.uniprot.org/citations/1587794 | http://purl.uniprot.org/core/author | "Kawakamyi K."xsd:string |
http://purl.uniprot.org/citations/1587794 | http://purl.uniprot.org/core/author | "Kawakamyi K."xsd:string |
http://purl.uniprot.org/citations/1587794 | http://purl.uniprot.org/core/date | "1992"xsd:gYear |
http://purl.uniprot.org/citations/1587794 | http://purl.uniprot.org/core/date | "1992"xsd:gYear |
http://purl.uniprot.org/citations/1587794 | http://purl.uniprot.org/core/name | "J. Biochem."xsd:string |
http://purl.uniprot.org/citations/1587794 | http://purl.uniprot.org/core/name | "J. Biochem."xsd:string |
http://purl.uniprot.org/citations/1587794 | http://purl.uniprot.org/core/pages | "331-336"xsd:string |
http://purl.uniprot.org/citations/1587794 | http://purl.uniprot.org/core/pages | "331-336"xsd:string |
http://purl.uniprot.org/citations/1587794 | http://purl.uniprot.org/core/title | "Molecular cloning and expression of cDNA encoding a galactose/N-acetylgalactosamine-specific lectin on mouse tumoricidal macrophages."xsd:string |
http://purl.uniprot.org/citations/1587794 | http://purl.uniprot.org/core/title | "Molecular cloning and expression of cDNA encoding a galactose/N-acetylgalactosamine-specific lectin on mouse tumoricidal macrophages."xsd:string |
http://purl.uniprot.org/citations/1587794 | http://purl.uniprot.org/core/volume | "111"xsd:string |
http://purl.uniprot.org/citations/1587794 | http://purl.uniprot.org/core/volume | "111"xsd:string |
http://purl.uniprot.org/citations/1587794 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/1587794 |
http://purl.uniprot.org/citations/1587794 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/1587794 |