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http://purl.uniprot.org/citations/1587864http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/1587864http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/1587864http://www.w3.org/2000/01/rdf-schema#comment"The two transcription activation functions (TAFs) of the human progesterone receptor (hPR) have been characterized. TAF-1, located in the N-terminal region A/B, has been narrowed down to a 91-amino acid sequence, which is sufficient for transcription activation in chimeras with the GAL4 DNA binding domain. Both hPR TAF-1 and TAF-2 activate a minimal promoter in yeast. No autonomous TAF could be found in the N-terminal 164 amino acids (designated AB3) which are responsible for the differential activation of promoters by the hPR isoforms A and B. Reduction of the target gene promoter complexity did not alter this differential activation, indicating that AB3 does not require additional promoter-bound factors to exert its effect. Instead, the cell specificity of AB3 and its ability to squelch hPR-induced transcription suggest that this differential isoform activity is due to the effect of a limiting factor which binds to region AB3."xsd:string
http://purl.uniprot.org/citations/1587864http://purl.org/dc/terms/identifier"doi:10.1016/s0021-9258(19)50100-4"xsd:string
http://purl.uniprot.org/citations/1587864http://purl.org/dc/terms/identifier"doi:10.1016/s0021-9258(19)50100-4"xsd:string
http://purl.uniprot.org/citations/1587864http://purl.uniprot.org/core/author"Meyer M.E."xsd:string
http://purl.uniprot.org/citations/1587864http://purl.uniprot.org/core/author"Meyer M.E."xsd:string
http://purl.uniprot.org/citations/1587864http://purl.uniprot.org/core/author"Gronemeyer H."xsd:string
http://purl.uniprot.org/citations/1587864http://purl.uniprot.org/core/author"Gronemeyer H."xsd:string
http://purl.uniprot.org/citations/1587864http://purl.uniprot.org/core/author"Lerouge T."xsd:string
http://purl.uniprot.org/citations/1587864http://purl.uniprot.org/core/author"Lerouge T."xsd:string
http://purl.uniprot.org/citations/1587864http://purl.uniprot.org/core/author"Bocquel M.T."xsd:string
http://purl.uniprot.org/citations/1587864http://purl.uniprot.org/core/author"Bocquel M.T."xsd:string
http://purl.uniprot.org/citations/1587864http://purl.uniprot.org/core/author"Quirin-Stricker C."xsd:string
http://purl.uniprot.org/citations/1587864http://purl.uniprot.org/core/author"Quirin-Stricker C."xsd:string
http://purl.uniprot.org/citations/1587864http://purl.uniprot.org/core/date"1992"xsd:gYear
http://purl.uniprot.org/citations/1587864http://purl.uniprot.org/core/date"1992"xsd:gYear
http://purl.uniprot.org/citations/1587864http://purl.uniprot.org/core/name"J. Biol. Chem."xsd:string
http://purl.uniprot.org/citations/1587864http://purl.uniprot.org/core/name"J. Biol. Chem."xsd:string
http://purl.uniprot.org/citations/1587864http://purl.uniprot.org/core/pages"10882-10887"xsd:string
http://purl.uniprot.org/citations/1587864http://purl.uniprot.org/core/pages"10882-10887"xsd:string
http://purl.uniprot.org/citations/1587864http://purl.uniprot.org/core/title"A limiting factor mediates the differential activation of promoters by the human progesterone receptor isoforms."xsd:string
http://purl.uniprot.org/citations/1587864http://purl.uniprot.org/core/title"A limiting factor mediates the differential activation of promoters by the human progesterone receptor isoforms."xsd:string
http://purl.uniprot.org/citations/1587864http://purl.uniprot.org/core/volume"267"xsd:string
http://purl.uniprot.org/citations/1587864http://purl.uniprot.org/core/volume"267"xsd:string