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http://purl.uniprot.org/citations/15880112http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/15880112http://www.w3.org/2000/01/rdf-schema#comment"The molecular mechanisms that direct the migration of early T lymphocyte progenitors to the thymus are unknown. We show here that P-selectin is expressed by thymic endothelium and that lymphoid progenitors in bone marrow and thymus bind P-selectin. Parabiosis, competitive thymus reconstitution and short-term homing assays indicated that P-selectin and its ligand PSGL-1 are functionally important components of the thymic homing process. Accordingly, thymi of mice lacking PSGL-1 contained fewer early thymic progenitors and had increased empty niches for prothymocytes compared with wild-type mice. Furthermore, the number of resident thymic progenitors controls thymic expression of P-selectin, suggesting that regulation of P-selectin expression by a thymic 'niche occupancy sensor' may be used to direct progenitor access."xsd:string
http://purl.uniprot.org/citations/15880112http://purl.org/dc/terms/identifier"doi:10.1038/ni1203"xsd:string
http://purl.uniprot.org/citations/15880112http://purl.uniprot.org/core/author"Yi L."xsd:string
http://purl.uniprot.org/citations/15880112http://purl.uniprot.org/core/author"Ziltener H.J."xsd:string
http://purl.uniprot.org/citations/15880112http://purl.uniprot.org/core/author"Carlow D.A."xsd:string
http://purl.uniprot.org/citations/15880112http://purl.uniprot.org/core/author"Corbel S.Y."xsd:string
http://purl.uniprot.org/citations/15880112http://purl.uniprot.org/core/author"So L."xsd:string
http://purl.uniprot.org/citations/15880112http://purl.uniprot.org/core/author"Rossi F.M."xsd:string
http://purl.uniprot.org/citations/15880112http://purl.uniprot.org/core/author"Merzaban J.S."xsd:string
http://purl.uniprot.org/citations/15880112http://purl.uniprot.org/core/author"Duenas J."xsd:string
http://purl.uniprot.org/citations/15880112http://purl.uniprot.org/core/author"Gossens K."xsd:string
http://purl.uniprot.org/citations/15880112http://purl.uniprot.org/core/date"2005"xsd:gYear
http://purl.uniprot.org/citations/15880112http://purl.uniprot.org/core/name"Nat Immunol"xsd:string
http://purl.uniprot.org/citations/15880112http://purl.uniprot.org/core/pages"626-634"xsd:string
http://purl.uniprot.org/citations/15880112http://purl.uniprot.org/core/title"Recruitment of adult thymic progenitors is regulated by P-selectin and its ligand PSGL-1."xsd:string
http://purl.uniprot.org/citations/15880112http://purl.uniprot.org/core/volume"6"xsd:string
http://purl.uniprot.org/citations/15880112http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/15880112
http://purl.uniprot.org/citations/15880112http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/15880112
http://purl.uniprot.org/uniprot/#_A0A0J9YTY7-mappedCitation-15880112http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15880112
http://purl.uniprot.org/uniprot/#_A0A0J9YUH7-mappedCitation-15880112http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15880112
http://purl.uniprot.org/uniprot/#_A0A0J9YV23-mappedCitation-15880112http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15880112
http://purl.uniprot.org/uniprot/#_A0A0G2JF74-mappedCitation-15880112http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15880112
http://purl.uniprot.org/uniprot/#_F6TL88-mappedCitation-15880112http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15880112
http://purl.uniprot.org/uniprot/#_Q62170-mappedCitation-15880112http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15880112