| http://purl.uniprot.org/citations/15882971 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15882971 | http://www.w3.org/2000/01/rdf-schema#comment | "The expression of core 2 beta1,6-N-acetylglucosaminyltransferase-1 (C2GnT) is associated with development and progression of malignancy. Sequence analysis showed that the codon 152 of C2GnT has a polymorphism having GTT encoding valine or ATT encoding isoleucine. By examining the polymorphism in prostate cancer and benign prostatic hyperplasia patients, we found that the C2GnT G allele was more frequently observed in the prostate cancer group (p=0.015) than the control group. Men with the GG genotype had a 3.60-fold increased risk of prostate cancer, and men with the AG genotype had a 1.58-fold increased risk of prostate cancer compared with those with the AA genotype. The G allele was found to have a gene dosage effect for prostate cancer risk. No such risk was associated for benign prostatic hyperplasia. These results demonstrate that C2GnT A/G polymorphism is associated with the susceptibility to prostate cancer in a Japanese population."xsd:string |
| http://purl.uniprot.org/citations/15882971 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.bbrc.2005.04.022"xsd:string |
| http://purl.uniprot.org/citations/15882971 | http://purl.uniprot.org/core/author | "Fukuda M."xsd:string |
| http://purl.uniprot.org/citations/15882971 | http://purl.uniprot.org/core/author | "Narita S."xsd:string |
| http://purl.uniprot.org/citations/15882971 | http://purl.uniprot.org/core/author | "Wang L."xsd:string |
| http://purl.uniprot.org/citations/15882971 | http://purl.uniprot.org/core/author | "Horikawa Y."xsd:string |
| http://purl.uniprot.org/citations/15882971 | http://purl.uniprot.org/core/author | "Imai A."xsd:string |
| http://purl.uniprot.org/citations/15882971 | http://purl.uniprot.org/core/author | "Habuchi T."xsd:string |
| http://purl.uniprot.org/citations/15882971 | http://purl.uniprot.org/core/author | "Tsuchiya N."xsd:string |
| http://purl.uniprot.org/citations/15882971 | http://purl.uniprot.org/core/author | "Ohyama C."xsd:string |
| http://purl.uniprot.org/citations/15882971 | http://purl.uniprot.org/core/author | "Mitoma J."xsd:string |
| http://purl.uniprot.org/citations/15882971 | http://purl.uniprot.org/core/author | "Ishimura H."xsd:string |
| http://purl.uniprot.org/citations/15882971 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
| http://purl.uniprot.org/citations/15882971 | http://purl.uniprot.org/core/name | "Biochem Biophys Res Commun"xsd:string |
| http://purl.uniprot.org/citations/15882971 | http://purl.uniprot.org/core/pages | "958-963"xsd:string |
| http://purl.uniprot.org/citations/15882971 | http://purl.uniprot.org/core/title | "An A/G polymorphism of core 2 branching enzyme gene is associated with prostate cancer."xsd:string |
| http://purl.uniprot.org/citations/15882971 | http://purl.uniprot.org/core/volume | "331"xsd:string |
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| http://purl.uniprot.org/citations/15882971 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/15882971 |
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| http://purl.uniprot.org/uniprot/#_Q02742-mappedCitation-15882971 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15882971 |