| http://purl.uniprot.org/citations/15884126 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15884126 | http://www.w3.org/2000/01/rdf-schema#comment | "AimTo elucidate the relations between the myeloperoxidase (-468)G-->A polymorphism and the development of duodenal ulcer (DU), and to investigate the impacts of this host genetic polymorphism on the histopathological features of Helicobacter pylori (H pylori)-related gastritis.MethodsIn a case-control study of 115 consecutive DU patients and 182 controls, the myeloperoxidase (-468)G-->A polymorphism was genotyped. Additionally, gastric mucosal changes were examined according to the updated Sydney System.ResultsThe two study groups differed in the distributions of myeloperoxidase genotypes (P = 0.008). All six individuals carrying myeloperoxidase A/A genotypes were in the DU group. The carriage of myeloperoxidase allele A and H pylori infection were associated with an increased risk of DU with odds ratios (OR) of 2.3 and 5.8, respectively. The combined risk of the carriage of myeloperoxidase allele A and H pylori infection for DU was 8.7 (95% CI, 3.5-21.8). In the H pylori-infected individuals, allele A carriers displayed higher bacterial density scores (P = 0.04) in the antrum than did non-carriers.ConclusionThis work verifies for the first time the association of myeloperoxidase (-468)G-->A polymorphism with antral H pylori density and DU disease. The mechanisms underlying this genetic polymorphism in developing DU disease merit further investigations."xsd:string |
| http://purl.uniprot.org/citations/15884126 | http://purl.org/dc/terms/identifier | "doi:10.3748/wjg.v11.i18.2796"xsd:string |
| http://purl.uniprot.org/citations/15884126 | http://purl.uniprot.org/core/author | "Chen A."xsd:string |
| http://purl.uniprot.org/citations/15884126 | http://purl.uniprot.org/core/author | "Wu C.J."xsd:string |
| http://purl.uniprot.org/citations/15884126 | http://purl.uniprot.org/core/author | "Chen J.L."xsd:string |
| http://purl.uniprot.org/citations/15884126 | http://purl.uniprot.org/core/author | "Chen Y.S."xsd:string |
| http://purl.uniprot.org/citations/15884126 | http://purl.uniprot.org/core/author | "Lo C.C."xsd:string |
| http://purl.uniprot.org/citations/15884126 | http://purl.uniprot.org/core/author | "Hsu P.I."xsd:string |
| http://purl.uniprot.org/citations/15884126 | http://purl.uniprot.org/core/author | "Hwang I.R."xsd:string |
| http://purl.uniprot.org/citations/15884126 | http://purl.uniprot.org/core/author | "Lai K.H."xsd:string |
| http://purl.uniprot.org/citations/15884126 | http://purl.uniprot.org/core/author | "Lo G.H."xsd:string |
| http://purl.uniprot.org/citations/15884126 | http://purl.uniprot.org/core/author | "Tseng H.H."xsd:string |
| http://purl.uniprot.org/citations/15884126 | http://purl.uniprot.org/core/author | "Chuah S.K."xsd:string |
| http://purl.uniprot.org/citations/15884126 | http://purl.uniprot.org/core/author | "Jwo J.J."xsd:string |
| http://purl.uniprot.org/citations/15884126 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
| http://purl.uniprot.org/citations/15884126 | http://purl.uniprot.org/core/name | "World J Gastroenterol"xsd:string |
| http://purl.uniprot.org/citations/15884126 | http://purl.uniprot.org/core/pages | "2796-2801"xsd:string |
| http://purl.uniprot.org/citations/15884126 | http://purl.uniprot.org/core/title | "Association of the myeloperoxidase -468G-->A polymorphism with gastric inflammation and duodenal ulcer risk."xsd:string |
| http://purl.uniprot.org/citations/15884126 | http://purl.uniprot.org/core/volume | "11"xsd:string |
| http://purl.uniprot.org/citations/15884126 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/15884126 |
| http://purl.uniprot.org/citations/15884126 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/15884126 |
| http://purl.uniprot.org/uniprot/#_A2NU82-mappedCitation-15884126 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15884126 |
| http://purl.uniprot.org/uniprot/#_P05164-mappedCitation-15884126 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15884126 |
| http://purl.uniprot.org/uniprot/#_Q16771-mappedCitation-15884126 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15884126 |