| http://purl.uniprot.org/citations/15894167 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15894167 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15894167 | http://www.w3.org/2000/01/rdf-schema#comment | "The production, survival, and function of monocytes and macrophages are regulated by the macrophage colony-stimulating factor (M-CSF or CSF-1) through its tyrosine kinase receptor. M-CSF receptor activates multiple cytoplasmic pathways in which adaptor and scaffolding proteins play a central role. In this study, we showed that SKAP55-related (SKAP55R) adaptor protein is expressed in myeloid cells and macrophages and is rapidly and transiently tyrosine-phosphorylated in response to M-CSF. M-CSF induced SKAP55R association with other tyrosine-phosphorylated proteins and with actin. When overexpressed in myeloid cells, SKAP55R decreased M-CSF-dependent proliferation without affecting differentiation. Altogether, these results demonstrate that SKAP55R adaptor is implicated in the M-CSF signaling pathway and suggest its role as a negative regulator of growth. Moreover, specific association between SKAP55R and actin support the idea that SKAP55R is implicated in the regulation of actin dynamics under the control of M-CSF."xsd:string |
| http://purl.uniprot.org/citations/15894167 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.cellsig.2004.11.009"xsd:string |
| http://purl.uniprot.org/citations/15894167 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.cellsig.2004.11.009"xsd:string |
| http://purl.uniprot.org/citations/15894167 | http://purl.uniprot.org/core/author | "Bourette R.P."xsd:string |
| http://purl.uniprot.org/citations/15894167 | http://purl.uniprot.org/core/author | "Bourette R.P."xsd:string |
| http://purl.uniprot.org/citations/15894167 | http://purl.uniprot.org/core/author | "Mouchiroud G."xsd:string |
| http://purl.uniprot.org/citations/15894167 | http://purl.uniprot.org/core/author | "Mouchiroud G."xsd:string |
| http://purl.uniprot.org/citations/15894167 | http://purl.uniprot.org/core/author | "Therier J."xsd:string |
| http://purl.uniprot.org/citations/15894167 | http://purl.uniprot.org/core/author | "Therier J."xsd:string |
| http://purl.uniprot.org/citations/15894167 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
| http://purl.uniprot.org/citations/15894167 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
| http://purl.uniprot.org/citations/15894167 | http://purl.uniprot.org/core/name | "Cell. Signal."xsd:string |
| http://purl.uniprot.org/citations/15894167 | http://purl.uniprot.org/core/name | "Cell. Signal."xsd:string |
| http://purl.uniprot.org/citations/15894167 | http://purl.uniprot.org/core/pages | "941-949"xsd:string |
| http://purl.uniprot.org/citations/15894167 | http://purl.uniprot.org/core/pages | "941-949"xsd:string |
| http://purl.uniprot.org/citations/15894167 | http://purl.uniprot.org/core/title | "Macrophage colony-stimulating factor receptor induces tyrosine phosphorylation of SKAP55R adaptor and its association with actin."xsd:string |
| http://purl.uniprot.org/citations/15894167 | http://purl.uniprot.org/core/title | "Macrophage colony-stimulating factor receptor induces tyrosine phosphorylation of SKAP55R adaptor and its association with actin."xsd:string |
| http://purl.uniprot.org/citations/15894167 | http://purl.uniprot.org/core/volume | "17"xsd:string |
| http://purl.uniprot.org/citations/15894167 | http://purl.uniprot.org/core/volume | "17"xsd:string |
| http://purl.uniprot.org/citations/15894167 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/15894167 |
| http://purl.uniprot.org/citations/15894167 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/15894167 |
| http://purl.uniprot.org/citations/15894167 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/15894167 |
| http://purl.uniprot.org/citations/15894167 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/15894167 |