| http://purl.uniprot.org/citations/15899409 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15899409 | http://www.w3.org/2000/01/rdf-schema#comment | "We studied whether complement receptor (CR) mediated Mycobacterium avium interaction modulated macrophage TNF-alpha expression. Compared to control conditions, infections performed with C3-depletion yielded significantly higher TNF-alpha levels. Blockage of the CR4 iC3b site yielded increases in TNF-alpha for all morphotypic variants of a virulent serovar-8 strain (smooth transparent (SmT), smooth opaque (SmO), serovar-specific glycopeptidolipid (ssGPL) deficient knockout mutant) whereas CR3 blockage increased TNF-alpha only for SmT and ssGPL-deficient strains. Thus, complement-mediated binding of M. avium to CR3 and CR4 was shown to modulate TNF-alpha expression. The differential activation of morphotypic and isogenic variants of a single strain provides an excellent model system to delineate signaling pathways."xsd:string |
| http://purl.uniprot.org/citations/15899409 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.femsle.2005.04.008"xsd:string |
| http://purl.uniprot.org/citations/15899409 | http://purl.uniprot.org/core/author | "Maslow J.N."xsd:string |
| http://purl.uniprot.org/citations/15899409 | http://purl.uniprot.org/core/author | "Irani V.R."xsd:string |
| http://purl.uniprot.org/citations/15899409 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
| http://purl.uniprot.org/citations/15899409 | http://purl.uniprot.org/core/name | "FEMS Microbiol Lett"xsd:string |
| http://purl.uniprot.org/citations/15899409 | http://purl.uniprot.org/core/pages | "221-228"xsd:string |
| http://purl.uniprot.org/citations/15899409 | http://purl.uniprot.org/core/title | "Induction of murine macrophage TNF-alpha synthesis by Mycobacterium avium is modulated through complement-dependent interaction via complement receptors 3 and 4 in relation to M. avium glycopeptidolipid."xsd:string |
| http://purl.uniprot.org/citations/15899409 | http://purl.uniprot.org/core/volume | "246"xsd:string |
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