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http://purl.uniprot.org/citations/15901498 | http://www.w3.org/2000/01/rdf-schema#comment | "Ribosomes, the large RNPs that translate mRNA into protein in the cytoplasm of eukaryotic cells, are synthesized in a subcompartment of the nucleus, the nucleolus. There, transcription by Pol I yields a pre-rRNA which is modified, cleaved and assembled with ribosomal proteins to make functional ribosomes. Previously, rRNA transcription and pre-rRNA cleavage in eukaryotes were considered to be separable steps in gene expression. However, recent findings suggest that these two steps in gene expression can be concurrent and are co-regulated. Unexpectedly, optimal rDNA transcription requires the presence of a defined subset of components of the pre-rRNA processing machinery."xsd:string |
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http://purl.uniprot.org/citations/15901498 | http://purl.uniprot.org/core/author | "Baserga S.J."xsd:string |
http://purl.uniprot.org/citations/15901498 | http://purl.uniprot.org/core/author | "Granneman S."xsd:string |
http://purl.uniprot.org/citations/15901498 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
http://purl.uniprot.org/citations/15901498 | http://purl.uniprot.org/core/name | "Curr Opin Cell Biol"xsd:string |
http://purl.uniprot.org/citations/15901498 | http://purl.uniprot.org/core/pages | "281-286"xsd:string |
http://purl.uniprot.org/citations/15901498 | http://purl.uniprot.org/core/title | "Crosstalk in gene expression: coupling and co-regulation of rDNA transcription, pre-ribosome assembly and pre-rRNA processing."xsd:string |
http://purl.uniprot.org/citations/15901498 | http://purl.uniprot.org/core/volume | "17"xsd:string |
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