| http://purl.uniprot.org/citations/15905587 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15905587 | http://www.w3.org/2000/01/rdf-schema#comment | "Focal adhesion kinase (FAK) is a nonreceptor protein tyrosine kinase involved in signaling downstream of integrins, linking bacterial detection, cell entry, and initiation of proinflammatory response through MAPKs and NF-kappaB activation. In this study, using protein I/II from Streptococcus mutans as a model activator of FAK, we investigated the potential link between FAK and TLR pathways. Using macrophages from TLR- or MyD88-deficient mice, we report that MyD88 plays a major role in FAK-dependent protein I/II-induced cytokine release. However, response to protein I/II stimulation was independent of TLR4, TLR2, and TLR6. The data suggest that there is a cross talk between FAK and MyD88 signaling pathways. Moreover, MyD88-dependent, LPS-induced IL-6 secretion by human and murine fibroblasts required the presence of FAK, confirming that MyD88 and FAK pathways are interlinked."xsd:string |
| http://purl.uniprot.org/citations/15905587 | http://purl.org/dc/terms/identifier | "doi:10.4049/jimmunol.174.11.7393"xsd:string |
| http://purl.uniprot.org/citations/15905587 | http://purl.uniprot.org/core/author | "Zeisel M.B."xsd:string |
| http://purl.uniprot.org/citations/15905587 | http://purl.uniprot.org/core/author | "Sibilia J."xsd:string |
| http://purl.uniprot.org/citations/15905587 | http://purl.uniprot.org/core/author | "Wachsmann D."xsd:string |
| http://purl.uniprot.org/citations/15905587 | http://purl.uniprot.org/core/author | "Klein J.P."xsd:string |
| http://purl.uniprot.org/citations/15905587 | http://purl.uniprot.org/core/author | "Quesniaux V."xsd:string |
| http://purl.uniprot.org/citations/15905587 | http://purl.uniprot.org/core/author | "Druet V.A."xsd:string |
| http://purl.uniprot.org/citations/15905587 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
| http://purl.uniprot.org/citations/15905587 | http://purl.uniprot.org/core/name | "J Immunol"xsd:string |
| http://purl.uniprot.org/citations/15905587 | http://purl.uniprot.org/core/pages | "7393-7397"xsd:string |
| http://purl.uniprot.org/citations/15905587 | http://purl.uniprot.org/core/title | "Cross talk between MyD88 and focal adhesion kinase pathways."xsd:string |
| http://purl.uniprot.org/citations/15905587 | http://purl.uniprot.org/core/volume | "174"xsd:string |
| http://purl.uniprot.org/citations/15905587 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/15905587 |
| http://purl.uniprot.org/citations/15905587 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/15905587 |
| http://purl.uniprot.org/uniprot/#_A0A0J9YTV4-mappedCitation-15905587 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15905587 |
| http://purl.uniprot.org/uniprot/#_Q0PM14-mappedCitation-15905587 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15905587 |
| http://purl.uniprot.org/uniprot/#_Q0PM15-mappedCitation-15905587 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15905587 |
| http://purl.uniprot.org/uniprot/#_Q0PM16-mappedCitation-15905587 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15905587 |
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| http://purl.uniprot.org/uniprot/#_A0A5F8MPY3-mappedCitation-15905587 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15905587 |
| http://purl.uniprot.org/uniprot/#_A0A2I3BPK4-mappedCitation-15905587 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15905587 |
| http://purl.uniprot.org/uniprot/#_A0A2I3BQ85-mappedCitation-15905587 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15905587 |
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