| http://purl.uniprot.org/citations/15907481 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15907481 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15907481 | http://www.w3.org/2000/01/rdf-schema#comment | "An immunoproteasome subunit low molecular weight protein 7 (LMP7) plays critical roles in major histocompatibility complex class I antigen processing; however, the mechanism for its expression has remained unclear. We demonstrate that interferon (IFN) regulatory factor-1 (IRF-1) has a pivotal role in IFN-gamma-dependent LMP7 expression, as was shown for the other two immunosubunits. A tetracycline-inducible system for IRF-1 revealed its function in the LMP7 expression, and a genomic region functionally interacting with IRF-1 was also determined. Furthermore, the role of IRF-1 in IFN-gamma-inducible LMP7 transcription was confirmed by employing small interfering RNA experiments and IRF-1-/-mice. These results suggest that IRF-1 acts as a master regulator for the concerted expression of immunoproteasome components."xsd:string |
| http://purl.uniprot.org/citations/15907481 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2005.04.012"xsd:string |
| http://purl.uniprot.org/citations/15907481 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2005.04.012"xsd:string |
| http://purl.uniprot.org/citations/15907481 | http://purl.uniprot.org/core/author | "Nakamura T."xsd:string |
| http://purl.uniprot.org/citations/15907481 | http://purl.uniprot.org/core/author | "Nakamura T."xsd:string |
| http://purl.uniprot.org/citations/15907481 | http://purl.uniprot.org/core/author | "Tsuchiya K."xsd:string |
| http://purl.uniprot.org/citations/15907481 | http://purl.uniprot.org/core/author | "Tsuchiya K."xsd:string |
| http://purl.uniprot.org/citations/15907481 | http://purl.uniprot.org/core/author | "Yamazaki M."xsd:string |
| http://purl.uniprot.org/citations/15907481 | http://purl.uniprot.org/core/author | "Yamazaki M."xsd:string |
| http://purl.uniprot.org/citations/15907481 | http://purl.uniprot.org/core/author | "Watanabe M."xsd:string |
| http://purl.uniprot.org/citations/15907481 | http://purl.uniprot.org/core/author | "Watanabe M."xsd:string |
| http://purl.uniprot.org/citations/15907481 | http://purl.uniprot.org/core/author | "Kanai T."xsd:string |
| http://purl.uniprot.org/citations/15907481 | http://purl.uniprot.org/core/author | "Kanai T."xsd:string |
| http://purl.uniprot.org/citations/15907481 | http://purl.uniprot.org/core/author | "Oshima S."xsd:string |
| http://purl.uniprot.org/citations/15907481 | http://purl.uniprot.org/core/author | "Oshima S."xsd:string |
| http://purl.uniprot.org/citations/15907481 | http://purl.uniprot.org/core/author | "Okamoto R."xsd:string |
| http://purl.uniprot.org/citations/15907481 | http://purl.uniprot.org/core/author | "Okamoto R."xsd:string |
| http://purl.uniprot.org/citations/15907481 | http://purl.uniprot.org/core/author | "Sekine Y."xsd:string |
| http://purl.uniprot.org/citations/15907481 | http://purl.uniprot.org/core/author | "Sekine Y."xsd:string |
| http://purl.uniprot.org/citations/15907481 | http://purl.uniprot.org/core/author | "Namiki S."xsd:string |
| http://purl.uniprot.org/citations/15907481 | http://purl.uniprot.org/core/author | "Namiki S."xsd:string |
| http://purl.uniprot.org/citations/15907481 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
| http://purl.uniprot.org/citations/15907481 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |