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http://purl.uniprot.org/citations/15908298http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/15908298http://www.w3.org/2000/01/rdf-schema#comment"We analyzed 100 control individuals and 60 patients with psoriasis vulgaris from the population of Campinas, Brazil. Typification of class II HLA alleles (HLA-DRB1-5 and -DQB1) was carried out through the DNA/PCR/SSP at medium and high resolution. DNA was extracted through a salting-out procedure: 13 DRB1 alleles, 3 DRB3 alleles, 1 DRB4 allele, 2 DRB5 alleles, and 5 DQB1 alleles were identified at a medium resolution using the PCR/SSP, and 45 DRB1 alleles were identified at a high resolution in analyzed patients. Results showed associations with psoriasis vulgaris: positive associations HLA-DRB3*02 (p < 0.05, chi(2) = 5.10, RR = 2.14); HLA-DRB1*0102 alleles (p < 0.05, RR = 5.44). Negative associations were found for HLA-DRB4*01 (chi(2) = 3.23, RR = 0.55) and HLA-DRB1*1302 alleles (p < 0.05, RR = 0.23). The haplotypes revealed positive association for HLA-DRB1*0102/DQB1*05 (p < 0.05, RR = 5.44) and HLA-DRB1*0701/DQB1*03 alleles (p < 0.02, RR = 9.00). These findings suggest a possible association of the DRB1 allele with the group of patients showing an early onset of the illness, as well as an association with haplotypes HLA-DRB1*0102/DQB1*05 and HLA-DRB1*0701/DQB1*03."xsd:string
http://purl.uniprot.org/citations/15908298http://purl.uniprot.org/core/author"Magalhaes R.F."xsd:string
http://purl.uniprot.org/citations/15908298http://purl.uniprot.org/core/author"Magna L.A."xsd:string
http://purl.uniprot.org/citations/15908298http://purl.uniprot.org/core/author"Kraemer M.H."xsd:string
http://purl.uniprot.org/citations/15908298http://purl.uniprot.org/core/author"Cardoso C.B."xsd:string
http://purl.uniprot.org/citations/15908298http://purl.uniprot.org/core/author"Uthida-Tanaka A.M."xsd:string
http://purl.uniprot.org/citations/15908298http://purl.uniprot.org/core/date"2005"xsd:gYear
http://purl.uniprot.org/citations/15908298http://purl.uniprot.org/core/name"Eur J Dermatol"xsd:string
http://purl.uniprot.org/citations/15908298http://purl.uniprot.org/core/pages"159-163"xsd:string
http://purl.uniprot.org/citations/15908298http://purl.uniprot.org/core/title"Association between psoriasis vulgaris and MHC-DRB, -DQB genes as a contribution to disease diagnosis."xsd:string
http://purl.uniprot.org/citations/15908298http://purl.uniprot.org/core/volume"15"xsd:string
http://purl.uniprot.org/citations/15908298http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/15908298
http://purl.uniprot.org/citations/15908298http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/15908298
http://purl.uniprot.org/uniprot/#_A0A0A7C3H3-mappedCitation-15908298http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15908298
http://purl.uniprot.org/uniprot/#_A0A0A7C3I1-mappedCitation-15908298http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15908298
http://purl.uniprot.org/uniprot/#_A0A0A7C3I5-mappedCitation-15908298http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15908298
http://purl.uniprot.org/uniprot/#_A0A0E3DC97-mappedCitation-15908298http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15908298
http://purl.uniprot.org/uniprot/#_A0A0E3DC99-mappedCitation-15908298http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15908298
http://purl.uniprot.org/uniprot/#_A0A076L4M5-mappedCitation-15908298http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15908298
http://purl.uniprot.org/uniprot/#_A0A0A0WDZ3-mappedCitation-15908298http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15908298
http://purl.uniprot.org/uniprot/#_A0A0A7C7I5-mappedCitation-15908298http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15908298
http://purl.uniprot.org/uniprot/#_A0A0A7C853-mappedCitation-15908298http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15908298
http://purl.uniprot.org/uniprot/#_A0A0A7CAC7-mappedCitation-15908298http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15908298
http://purl.uniprot.org/uniprot/#_A0A0A7CAE0-mappedCitation-15908298http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15908298