| http://purl.uniprot.org/citations/15910750 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15910750 | http://www.w3.org/2000/01/rdf-schema#comment | "The potential association of CD2AP with the adherens junction protein E-cadherin, co-localization with the actin cytoskeleton, and involvement in cell migration was investigated in cultured rat gastric mucosal cells. In stationary cells, CD2AP was localized perinuclearly while E-cadherin was expressed along cell-cell contacts and F-actin formed a branched network and adhesion belts. In migrating cells, CD2AP appeared as thread-like accumulations in the leading edges, colocalizing with F-actin and occasionally with E-cadherin. Intracellular injection of anti-CD2AP significantly retarded the migration speed of the cells suggesting a crucial role for CD2AP in mucosal cell migration, possibly as a scaffolding protein between cell membrane proteins and actin cytoskeleton. Co-immunoprecipitation assays revealed that CD2AP and E-cadherin are in a complex in HGF stimulated cells. It is concluded that CD2AP interacts with E-cadherin and co-localizes with F-actin in the leading edge of migrating cells, and significantly contributes to cell migration in restituting gastric epithelium."xsd:string |
| http://purl.uniprot.org/citations/15910750 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.bbrc.2005.04.140"xsd:string |
| http://purl.uniprot.org/citations/15910750 | http://purl.uniprot.org/core/author | "Lehtonen S."xsd:string |
| http://purl.uniprot.org/citations/15910750 | http://purl.uniprot.org/core/author | "Lehtonen E."xsd:string |
| http://purl.uniprot.org/citations/15910750 | http://purl.uniprot.org/core/author | "Lepisto A."xsd:string |
| http://purl.uniprot.org/citations/15910750 | http://purl.uniprot.org/core/author | "Puolakkainen P."xsd:string |
| http://purl.uniprot.org/citations/15910750 | http://purl.uniprot.org/core/author | "Mustonen H."xsd:string |
| http://purl.uniprot.org/citations/15910750 | http://purl.uniprot.org/core/author | "Kivilaakso E."xsd:string |
| http://purl.uniprot.org/citations/15910750 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
| http://purl.uniprot.org/citations/15910750 | http://purl.uniprot.org/core/name | "Biochem Biophys Res Commun"xsd:string |
| http://purl.uniprot.org/citations/15910750 | http://purl.uniprot.org/core/pages | "426-432"xsd:string |
| http://purl.uniprot.org/citations/15910750 | http://purl.uniprot.org/core/title | "CD2AP contributes to cell migration and adhesion in cultured gastric epithelium."xsd:string |
| http://purl.uniprot.org/citations/15910750 | http://purl.uniprot.org/core/volume | "332"xsd:string |
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