| http://purl.uniprot.org/citations/15911379 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15911379 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15911379 | http://www.w3.org/2000/01/rdf-schema#comment | "Biotin synthase is an S-adenosyl-L-methionine (SAM) radical enzyme that inserts sulfur into dethiobiotin to produce biotin. The reaction proceeds through 5'-deoxyadenosyl radical intermediates that become reduced during the sulfur insertion step to give another product of the reaction, 5'-deoxyadenosine. We report that Escherichia coli strains lacking the 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase encoded by the pfs gene are deficient in biotin synthase activity due to accumulation of 5'-deoxyadenosine, a new substrate of the pfs-encoded nucleosidase. Physiological experiments indicate that lipoic acid synthase, another SAM radical enzyme, is also inhibited by 5'-deoxyadenosine accumulation."xsd:string |
| http://purl.uniprot.org/citations/15911379 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.chembiol.2005.04.012"xsd:string |
| http://purl.uniprot.org/citations/15911379 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.chembiol.2005.04.012"xsd:string |
| http://purl.uniprot.org/citations/15911379 | http://purl.uniprot.org/core/author | "Cronan J.E."xsd:string |
| http://purl.uniprot.org/citations/15911379 | http://purl.uniprot.org/core/author | "Cronan J.E."xsd:string |
| http://purl.uniprot.org/citations/15911379 | http://purl.uniprot.org/core/author | "Choi-Rhee E."xsd:string |
| http://purl.uniprot.org/citations/15911379 | http://purl.uniprot.org/core/author | "Choi-Rhee E."xsd:string |
| http://purl.uniprot.org/citations/15911379 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
| http://purl.uniprot.org/citations/15911379 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
| http://purl.uniprot.org/citations/15911379 | http://purl.uniprot.org/core/name | "Chem. Biol."xsd:string |
| http://purl.uniprot.org/citations/15911379 | http://purl.uniprot.org/core/name | "Chem. Biol."xsd:string |
| http://purl.uniprot.org/citations/15911379 | http://purl.uniprot.org/core/pages | "589-593"xsd:string |
| http://purl.uniprot.org/citations/15911379 | http://purl.uniprot.org/core/pages | "589-593"xsd:string |
| http://purl.uniprot.org/citations/15911379 | http://purl.uniprot.org/core/title | "A nucleosidase required for in vivo function of the S-adenosyl-L-methionine radical enzyme, biotin synthase."xsd:string |
| http://purl.uniprot.org/citations/15911379 | http://purl.uniprot.org/core/title | "A nucleosidase required for in vivo function of the S-adenosyl-L-methionine radical enzyme, biotin synthase."xsd:string |
| http://purl.uniprot.org/citations/15911379 | http://purl.uniprot.org/core/volume | "12"xsd:string |
| http://purl.uniprot.org/citations/15911379 | http://purl.uniprot.org/core/volume | "12"xsd:string |
| http://purl.uniprot.org/citations/15911379 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/15911379 |
| http://purl.uniprot.org/citations/15911379 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/15911379 |
| http://purl.uniprot.org/citations/15911379 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/15911379 |
| http://purl.uniprot.org/citations/15911379 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/15911379 |
| http://purl.uniprot.org/uniprot/P12996 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/15911379 |
| http://purl.uniprot.org/uniprot/P0AF12 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/15911379 |