| http://purl.uniprot.org/citations/15924141 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15924141 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15924141 | http://www.w3.org/2000/01/rdf-schema#comment | "RNA-directed DNA methylation, one of several RNA interference-mediated pathways in the nucleus, has been documented in plants and in human cells. Despite progress in identifying the DNA methyltransferases, histone-modifying enzymes and RNA interference proteins needed for RNA-directed DNA methylation, the mechanism remains incompletely understood. We screened for mutants defective in RNA-directed DNA methylation and silencing of a transgene promoter in Arabidopsis thaliana and identified three drd complementation groups. DRD1 is a SNF2-like protein required for RNA-directed de novo methylation. We report here that DRD2 and DRD3 correspond to the second-largest subunit and largest subunit, respectively, of a fourth class of DNA-dependent RNA polymerase (polymerase IV) that is unique to plants. DRD3 is a functionally diversified homolog of NRPD1a or SDE4, identified in a separate screen for mutants defective in post-transcriptional gene silencing. The identical DNA methylation patterns observed in all three drd mutants suggest that DRD proteins cooperate to create a substrate for RNA-directed de novo methylation."xsd:string |
| http://purl.uniprot.org/citations/15924141 | http://purl.org/dc/terms/identifier | "doi:10.1038/ng1580"xsd:string |
| http://purl.uniprot.org/citations/15924141 | http://purl.org/dc/terms/identifier | "doi:10.1038/ng1580"xsd:string |
| http://purl.uniprot.org/citations/15924141 | http://purl.uniprot.org/core/author | "Huettel B."xsd:string |
| http://purl.uniprot.org/citations/15924141 | http://purl.uniprot.org/core/author | "Huettel B."xsd:string |
| http://purl.uniprot.org/citations/15924141 | http://purl.uniprot.org/core/author | "Kanno T."xsd:string |
| http://purl.uniprot.org/citations/15924141 | http://purl.uniprot.org/core/author | "Kanno T."xsd:string |
| http://purl.uniprot.org/citations/15924141 | http://purl.uniprot.org/core/author | "Aufsatz W."xsd:string |
| http://purl.uniprot.org/citations/15924141 | http://purl.uniprot.org/core/author | "Aufsatz W."xsd:string |
| http://purl.uniprot.org/citations/15924141 | http://purl.uniprot.org/core/author | "Daxinger L."xsd:string |
| http://purl.uniprot.org/citations/15924141 | http://purl.uniprot.org/core/author | "Daxinger L."xsd:string |
| http://purl.uniprot.org/citations/15924141 | http://purl.uniprot.org/core/author | "Jaligot E."xsd:string |
| http://purl.uniprot.org/citations/15924141 | http://purl.uniprot.org/core/author | "Jaligot E."xsd:string |
| http://purl.uniprot.org/citations/15924141 | http://purl.uniprot.org/core/author | "Kreil D.P."xsd:string |
| http://purl.uniprot.org/citations/15924141 | http://purl.uniprot.org/core/author | "Kreil D.P."xsd:string |
| http://purl.uniprot.org/citations/15924141 | http://purl.uniprot.org/core/author | "Matzke A.J.M."xsd:string |
| http://purl.uniprot.org/citations/15924141 | http://purl.uniprot.org/core/author | "Matzke A.J.M."xsd:string |
| http://purl.uniprot.org/citations/15924141 | http://purl.uniprot.org/core/author | "Matzke M."xsd:string |
| http://purl.uniprot.org/citations/15924141 | http://purl.uniprot.org/core/author | "Matzke M."xsd:string |
| http://purl.uniprot.org/citations/15924141 | http://purl.uniprot.org/core/author | "Mette M.F."xsd:string |
| http://purl.uniprot.org/citations/15924141 | http://purl.uniprot.org/core/author | "Mette M.F."xsd:string |
| http://purl.uniprot.org/citations/15924141 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
| http://purl.uniprot.org/citations/15924141 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |