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http://purl.uniprot.org/citations/15937486http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/15937486http://www.w3.org/2000/01/rdf-schema#comment"One unresolved issue in gut immunity is how mucosal T lymphocytes are activated and which antigen-presenting cell (APC) is critical for the regulation of this process. We have identified a unique population of APCs that is exclusively localized in the lamina propria. These APCs constitutively expressed the costimulatory molecule CD70 and had antigen-presenting functions. After oral infection of mice with Listeria monocytogenes, proliferation and differentiation of antigen-specific T cells occurred in the gut mucosa in situ and blockade of CD70 costimulation abrogated the mucosal T cell proliferation and effector functions. Thus, a potent CD70-dependent stimulation via specialized tissue-specific APCs is required for the proliferation and differentiation of gut mucosal T cells after oral infection."xsd:string
http://purl.uniprot.org/citations/15937486http://purl.org/dc/terms/identifier"doi:10.1038/ni1212"xsd:string
http://purl.uniprot.org/citations/15937486http://purl.uniprot.org/core/author"van Lier R.A."xsd:string
http://purl.uniprot.org/citations/15937486http://purl.uniprot.org/core/author"Vargas D."xsd:string
http://purl.uniprot.org/citations/15937486http://purl.uniprot.org/core/author"Manjunath N."xsd:string
http://purl.uniprot.org/citations/15937486http://purl.uniprot.org/core/author"Laouar A."xsd:string
http://purl.uniprot.org/citations/15937486http://purl.uniprot.org/core/author"Haridas V."xsd:string
http://purl.uniprot.org/citations/15937486http://purl.uniprot.org/core/author"Chaplin D."xsd:string
http://purl.uniprot.org/citations/15937486http://purl.uniprot.org/core/author"Zhinan X."xsd:string
http://purl.uniprot.org/citations/15937486http://purl.uniprot.org/core/date"2005"xsd:gYear
http://purl.uniprot.org/citations/15937486http://purl.uniprot.org/core/name"Nat Immunol"xsd:string
http://purl.uniprot.org/citations/15937486http://purl.uniprot.org/core/pages"698-706"xsd:string
http://purl.uniprot.org/citations/15937486http://purl.uniprot.org/core/title"CD70+ antigen-presenting cells control the proliferation and differentiation of T cells in the intestinal mucosa."xsd:string
http://purl.uniprot.org/citations/15937486http://purl.uniprot.org/core/volume"6"xsd:string
http://purl.uniprot.org/citations/15937486http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/15937486
http://purl.uniprot.org/citations/15937486http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/15937486
http://purl.uniprot.org/uniprot/#_A0A075B5P6-mappedCitation-15937486http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15937486
http://purl.uniprot.org/uniprot/#_A0A075B6A0-mappedCitation-15937486http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15937486
http://purl.uniprot.org/uniprot/#_O55237-mappedCitation-15937486http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15937486
http://purl.uniprot.org/uniprot/#_P15919-mappedCitation-15937486http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15937486
http://purl.uniprot.org/uniprot/#_Q05A52-mappedCitation-15937486http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15937486
http://purl.uniprot.org/uniprot/#_P09225-mappedCitation-15937486http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15937486
http://purl.uniprot.org/uniprot/#_P01872-mappedCitation-15937486http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15937486
http://purl.uniprot.org/uniprot/#_Q3TR87-mappedCitation-15937486http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15937486