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http://purl.uniprot.org/citations/15943789http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/15943789http://www.w3.org/2000/01/rdf-schema#comment"Although diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma, it is both clinically and morphologically heterogenous. The present study investigates the significance of survivin and a novel monoclonal antibody (MAb), T332, immunohistochemically for predicting the prognoses of DLBCL and its subtypes classified as germinal center B-cell-like type (GCB) and non-GCB type (NGCB) based on the expression profiles of CD10, bcl-6, and MUM1. A total of 60 cases of DLBCL (GCB, n = 22; NGCB, n = 38) were examined for the expression of survivin and T332 antigen. Survivin(+) DLBCL had a significantly worse prognosis (P = 0.01) than survivin(-) cases, as already reported, while survivin(+) GCB or NGCB tended to have poor prognoses (P = 0.06 and 0.07, respectively). However, T332(+) DLBCL and NGCB had significantly more unfavorable prognoses than T332(-) cases (P = 0.01 and 0.02, respectively) while there was no significant survival difference between the T332(+) and T332(-) groups of GCB (P = 0.11). Interestingly DLBCL coexpressing survivin and T332 (n = 13) had a significantly worse prognosis (P = 0.009) than the remaining single positive and double negative cases (n = 31). In conclusion, survivin and the novel MAb, T332, might be a good predictor of DLBCL and its subtypes."xsd:string
http://purl.uniprot.org/citations/15943789http://purl.org/dc/terms/identifier"doi:10.1111/j.1440-1827.2005.01832.x"xsd:string
http://purl.uniprot.org/citations/15943789http://purl.uniprot.org/core/author"Hara T."xsd:string
http://purl.uniprot.org/citations/15943789http://purl.uniprot.org/core/author"Goto N."xsd:string
http://purl.uniprot.org/citations/15943789http://purl.uniprot.org/core/author"Kojima Y."xsd:string
http://purl.uniprot.org/citations/15943789http://purl.uniprot.org/core/author"Tsurumi H."xsd:string
http://purl.uniprot.org/citations/15943789http://purl.uniprot.org/core/author"Takami T."xsd:string
http://purl.uniprot.org/citations/15943789http://purl.uniprot.org/core/author"Kasahara S."xsd:string
http://purl.uniprot.org/citations/15943789http://purl.uniprot.org/core/author"Moriwaki H."xsd:string
http://purl.uniprot.org/citations/15943789http://purl.uniprot.org/core/author"Saio M."xsd:string
http://purl.uniprot.org/citations/15943789http://purl.uniprot.org/core/author"Watanuki-Miyauchi R."xsd:string
http://purl.uniprot.org/citations/15943789http://purl.uniprot.org/core/date"2005"xsd:gYear
http://purl.uniprot.org/citations/15943789http://purl.uniprot.org/core/name"Pathol Int"xsd:string
http://purl.uniprot.org/citations/15943789http://purl.uniprot.org/core/pages"324-330"xsd:string
http://purl.uniprot.org/citations/15943789http://purl.uniprot.org/core/title"Expression of survivin and of antigen detected by a novel monoclonal antibody, T332, is associated with outcome of diffuse large B-cell lymphoma and its subtypes."xsd:string
http://purl.uniprot.org/citations/15943789http://purl.uniprot.org/core/volume"55"xsd:string
http://purl.uniprot.org/citations/15943789http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/15943789
http://purl.uniprot.org/citations/15943789http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/15943789
http://purl.uniprot.org/uniprot/#_A0A0B4J1S3-mappedCitation-15943789http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15943789
http://purl.uniprot.org/uniprot/#_A0A7L8XZM3-mappedCitation-15943789http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15943789
http://purl.uniprot.org/uniprot/#_A3E0Z5-mappedCitation-15943789http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15943789
http://purl.uniprot.org/uniprot/#_A3E0Z6-mappedCitation-15943789http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15943789
http://purl.uniprot.org/uniprot/#_A3E0Z7-mappedCitation-15943789http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15943789
http://purl.uniprot.org/uniprot/#_A3E0Z8-mappedCitation-15943789http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15943789