| http://purl.uniprot.org/citations/15950780 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15950780 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15950780 | http://www.w3.org/2000/01/rdf-schema#comment | "Interleukin-1 beta (IL-1) and CREB have many CNS actions including sleep regulation and hippocampal-dependent learning. CREB acts in part via CREB-binding protein (CBP). We thus determined whether IL-1 could induce CBP gene expression. Initially, cultured hippocampal cells were treated with IL-1 and differential display reverse transcription was used to identify up- and down-regulated genes. We then sequenced rat CBP. Of the IL-1-upregulated genes, CBP and adenine nucleotide translocator-1 (ANT-1) were investigated in vivo. In these experiments, IL-1 was given to rats intraventricularly and sacrificed 2 h later; both CBP and ANT-1 transcripts were upregulated in the cerebral cortex and hypothalamus. We conclude that rat CBP shares many of the functional domains as human and murine CBP and that IL-1 upregulates genes previously associated with learning and sleep."xsd:string |
| http://purl.uniprot.org/citations/15950780 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.molbrainres.2005.03.009"xsd:string |
| http://purl.uniprot.org/citations/15950780 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.molbrainres.2005.03.009"xsd:string |
| http://purl.uniprot.org/citations/15950780 | http://purl.uniprot.org/core/author | "Tang C."xsd:string |
| http://purl.uniprot.org/citations/15950780 | http://purl.uniprot.org/core/author | "Tang C."xsd:string |
| http://purl.uniprot.org/citations/15950780 | http://purl.uniprot.org/core/author | "Bohnet S."xsd:string |
| http://purl.uniprot.org/citations/15950780 | http://purl.uniprot.org/core/author | "Bohnet S."xsd:string |
| http://purl.uniprot.org/citations/15950780 | http://purl.uniprot.org/core/author | "Krueger J.M."xsd:string |
| http://purl.uniprot.org/citations/15950780 | http://purl.uniprot.org/core/author | "Krueger J.M."xsd:string |
| http://purl.uniprot.org/citations/15950780 | http://purl.uniprot.org/core/author | "Rehman A."xsd:string |
| http://purl.uniprot.org/citations/15950780 | http://purl.uniprot.org/core/author | "Rehman A."xsd:string |
| http://purl.uniprot.org/citations/15950780 | http://purl.uniprot.org/core/author | "Sula M.J."xsd:string |
| http://purl.uniprot.org/citations/15950780 | http://purl.uniprot.org/core/author | "Sula M.J."xsd:string |
| http://purl.uniprot.org/citations/15950780 | http://purl.uniprot.org/core/author | "Taishi P."xsd:string |
| http://purl.uniprot.org/citations/15950780 | http://purl.uniprot.org/core/author | "Taishi P."xsd:string |
| http://purl.uniprot.org/citations/15950780 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
| http://purl.uniprot.org/citations/15950780 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
| http://purl.uniprot.org/citations/15950780 | http://purl.uniprot.org/core/name | "Brain Res. Mol. Brain Res."xsd:string |
| http://purl.uniprot.org/citations/15950780 | http://purl.uniprot.org/core/name | "Brain Res. Mol. Brain Res."xsd:string |
| http://purl.uniprot.org/citations/15950780 | http://purl.uniprot.org/core/pages | "213-222"xsd:string |
| http://purl.uniprot.org/citations/15950780 | http://purl.uniprot.org/core/pages | "213-222"xsd:string |
| http://purl.uniprot.org/citations/15950780 | http://purl.uniprot.org/core/title | "Interleukin-1beta induces CREB-binding protein (CBP) mRNA in brain and the sequencing of rat CBP."xsd:string |
| http://purl.uniprot.org/citations/15950780 | http://purl.uniprot.org/core/title | "Interleukin-1beta induces CREB-binding protein (CBP) mRNA in brain and the sequencing of rat CBP."xsd:string |