| http://purl.uniprot.org/citations/15951434 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15951434 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15951434 | http://www.w3.org/2000/01/rdf-schema#comment | "Golgin-160 belongs to the golgin family of Golgi-localized proteins, which have been implicated in Golgi structure and function. Golgin-160 possesses an N-terminal non-coiled-coil "head" domain followed by an extensive coiled-coil region. Using the N-terminal head domain of golgin-160 as bait in a yeast two-hybrid screen, the postsynaptic density-95/Discs large/zona occludens-1 (PDZ) domain protein interacting specifically with TC10 (PIST) was identified to interact with golgin-160. PIST (also known as GOPC, CAL, and FIG) has been implicated in the trafficking of a subset of plasma membrane proteins, supporting a role of golgin-160 in vesicular trafficking. Golgin-160 and PIST colocalize to Golgi membranes and interact in vivo. Glutathione S-transferase binding experiments identified an internal region of PIST that includes a coiled-coil domain, which interacts directly with golgin-160. Similar binding experiments identified a leucine-rich repeat within golgin-160 necessary for interaction with PIST. Therefore, our data suggest that golgin-160 may participate in PIST-dependent trafficking of cargo. Interestingly, we also discovered a widely expressed isoform of golgin-160, golgin-160B, which lacks the exon encoding the leucine repeat that mediates binding to PIST. As predicted, golgin-160B was unable to bind PIST. Full-length golgin-160 and golgin-160B may link distinct subsets of proteins to effect specific membrane trafficking pathways."xsd:string |
| http://purl.uniprot.org/citations/15951434 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.m504937200"xsd:string |
| http://purl.uniprot.org/citations/15951434 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.m504937200"xsd:string |
| http://purl.uniprot.org/citations/15951434 | http://purl.uniprot.org/core/author | "Machamer C.E."xsd:string |
| http://purl.uniprot.org/citations/15951434 | http://purl.uniprot.org/core/author | "Machamer C.E."xsd:string |
| http://purl.uniprot.org/citations/15951434 | http://purl.uniprot.org/core/author | "Hicks S.W."xsd:string |
| http://purl.uniprot.org/citations/15951434 | http://purl.uniprot.org/core/author | "Hicks S.W."xsd:string |
| http://purl.uniprot.org/citations/15951434 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
| http://purl.uniprot.org/citations/15951434 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
| http://purl.uniprot.org/citations/15951434 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
| http://purl.uniprot.org/citations/15951434 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
| http://purl.uniprot.org/citations/15951434 | http://purl.uniprot.org/core/pages | "28944-28951"xsd:string |
| http://purl.uniprot.org/citations/15951434 | http://purl.uniprot.org/core/pages | "28944-28951"xsd:string |
| http://purl.uniprot.org/citations/15951434 | http://purl.uniprot.org/core/title | "Isoform-specific interaction of golgin-160 with the Golgi-associated protein PIST."xsd:string |
| http://purl.uniprot.org/citations/15951434 | http://purl.uniprot.org/core/title | "Isoform-specific interaction of golgin-160 with the Golgi-associated protein PIST."xsd:string |
| http://purl.uniprot.org/citations/15951434 | http://purl.uniprot.org/core/volume | "280"xsd:string |
| http://purl.uniprot.org/citations/15951434 | http://purl.uniprot.org/core/volume | "280"xsd:string |
| http://purl.uniprot.org/citations/15951434 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/15951434 |
| http://purl.uniprot.org/citations/15951434 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/15951434 |
| http://purl.uniprot.org/citations/15951434 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/15951434 |
| http://purl.uniprot.org/citations/15951434 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/15951434 |
| http://purl.uniprot.org/uniprot/Q08378 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/15951434 |
| http://purl.uniprot.org/uniprot/Q9HD26 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/15951434 |