| http://purl.uniprot.org/citations/15956708 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15956708 | http://www.w3.org/2000/01/rdf-schema#comment | "Knowledge of the distribution of the relaxin receptor, LGR7, in the brain provides a basis for studies of the physiologic actions of relaxin. LGR7 knock-out (KO) mice were produced by the in-frame replacement of LGR7 exon 10 and 11 with a LacZ-reporter cassette (knock-in [KI]), and in this study we used LGR7-KO/LacZ-KI mice to determine the regional/cellular distribution of LGR7 gene expression in adult mouse brain by assessing beta-galactosidase activity in perfusion-fixed sections. High densities of beta-galactosidase-positive neurons were detected in anterior olfactory and claustrum/endopiriform nuclei, deep layers of cortex (particularly somatosensory), and the subiculum. Low to moderate densities were detected in olfactory bulb (periglomerular layer), cingulate cortex, subfornical organ, hippocampal CA2/dentate hilus, amygdala, hypothalamus, and thalamus. This LGR7/LacZ expression appears to recapitulate that of native LGR7 in wild-type mice and provides a model to further investigate the phenotype of LGR7-responsive neurons in the brain and to help reveal functions associated with central relaxin signaling."xsd:string |
| http://purl.uniprot.org/citations/15956708 | http://purl.org/dc/terms/identifier | "doi:10.1196/annals.1282.030"xsd:string |
| http://purl.uniprot.org/citations/15956708 | http://purl.uniprot.org/core/author | "Ma S."xsd:string |
| http://purl.uniprot.org/citations/15956708 | http://purl.uniprot.org/core/author | "Gossen J.A."xsd:string |
| http://purl.uniprot.org/citations/15956708 | http://purl.uniprot.org/core/author | "Mosselman S."xsd:string |
| http://purl.uniprot.org/citations/15956708 | http://purl.uniprot.org/core/author | "Bathgate R.A."xsd:string |
| http://purl.uniprot.org/citations/15956708 | http://purl.uniprot.org/core/author | "Gundlach A.L."xsd:string |
| http://purl.uniprot.org/citations/15956708 | http://purl.uniprot.org/core/author | "Burazin T.C."xsd:string |
| http://purl.uniprot.org/citations/15956708 | http://purl.uniprot.org/core/author | "Shen P.J."xsd:string |
| http://purl.uniprot.org/citations/15956708 | http://purl.uniprot.org/core/author | "Piccenna L."xsd:string |
| http://purl.uniprot.org/citations/15956708 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
| http://purl.uniprot.org/citations/15956708 | http://purl.uniprot.org/core/name | "Ann N Y Acad Sci"xsd:string |
| http://purl.uniprot.org/citations/15956708 | http://purl.uniprot.org/core/pages | "197-204"xsd:string |
| http://purl.uniprot.org/citations/15956708 | http://purl.uniprot.org/core/title | "Localization of LGR7 gene expression in adult mouse brain using LGR7 knock-out/LacZ knock-in mice: correlation with LGR7 mRNA distribution."xsd:string |
| http://purl.uniprot.org/citations/15956708 | http://purl.uniprot.org/core/volume | "1041"xsd:string |
| http://purl.uniprot.org/citations/15956708 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/15956708 |
| http://purl.uniprot.org/citations/15956708 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/15956708 |
| http://purl.uniprot.org/uniprot/#_Q6R6I7-mappedCitation-15956708 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15956708 |
| http://purl.uniprot.org/uniprot/Q6R6I7 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/15956708 |