| http://purl.uniprot.org/citations/15961081 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15961081 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15961081 | http://www.w3.org/2000/01/rdf-schema#comment | "Reduced expression of pro-apoptotic Bcl-2 family proteins has been described in many gastrointestinal cancers, and may play a role in tumourigenesis. The human homologue of the pro-apoptotic Bcl-2 protein, Bfk, is predominantly expressed in tissues of the gastrointestinal tract. In colon, four alternatively spliced isoforms were identified; of which two are pro-apoptotic when overexpressed. In the transition from normal tissue to tumour, pro-apoptotic Bfk isoform expression is substantially reduced in up to 80% of tumours isolated from the human gastrointestinal tract (8/10 colonic tumours and 26/37 of all gastrointestinal tumours) compared to 3/117 tumours from outside the gastrointestinal tract. These data suggest that pro-apoptotic isoforms of Bfk may help to protect against the development of human gastrointestinal malignancy."xsd:string |
| http://purl.uniprot.org/citations/15961081 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2005.05.050"xsd:string |
| http://purl.uniprot.org/citations/15961081 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2005.05.050"xsd:string |
| http://purl.uniprot.org/citations/15961081 | http://purl.uniprot.org/core/author | "Dempsey C.E."xsd:string |
| http://purl.uniprot.org/citations/15961081 | http://purl.uniprot.org/core/author | "Dempsey C.E."xsd:string |
| http://purl.uniprot.org/citations/15961081 | http://purl.uniprot.org/core/author | "Bingle C.D."xsd:string |
| http://purl.uniprot.org/citations/15961081 | http://purl.uniprot.org/core/author | "Bingle C.D."xsd:string |
| http://purl.uniprot.org/citations/15961081 | http://purl.uniprot.org/core/author | "Barnes F.A."xsd:string |
| http://purl.uniprot.org/citations/15961081 | http://purl.uniprot.org/core/author | "Barnes F.A."xsd:string |
| http://purl.uniprot.org/citations/15961081 | http://purl.uniprot.org/core/author | "Dive C."xsd:string |
| http://purl.uniprot.org/citations/15961081 | http://purl.uniprot.org/core/author | "Dive C."xsd:string |
| http://purl.uniprot.org/citations/15961081 | http://purl.uniprot.org/core/author | "Fletcher D.J."xsd:string |
| http://purl.uniprot.org/citations/15961081 | http://purl.uniprot.org/core/author | "Fletcher D.J."xsd:string |
| http://purl.uniprot.org/citations/15961081 | http://purl.uniprot.org/core/author | "Lobo A."xsd:string |
| http://purl.uniprot.org/citations/15961081 | http://purl.uniprot.org/core/author | "Lobo A."xsd:string |
| http://purl.uniprot.org/citations/15961081 | http://purl.uniprot.org/core/author | "Renshaw S.A."xsd:string |
| http://purl.uniprot.org/citations/15961081 | http://purl.uniprot.org/core/author | "Renshaw S.A."xsd:string |
| http://purl.uniprot.org/citations/15961081 | http://purl.uniprot.org/core/author | "Whyte M.K."xsd:string |
| http://purl.uniprot.org/citations/15961081 | http://purl.uniprot.org/core/author | "Whyte M.K."xsd:string |
| http://purl.uniprot.org/citations/15961081 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
| http://purl.uniprot.org/citations/15961081 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
| http://purl.uniprot.org/citations/15961081 | http://purl.uniprot.org/core/name | "FEBS Lett."xsd:string |
| http://purl.uniprot.org/citations/15961081 | http://purl.uniprot.org/core/name | "FEBS Lett."xsd:string |