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http://purl.uniprot.org/citations/15963483http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/15963483http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/15963483http://www.w3.org/2000/01/rdf-schema#comment"We are reporting the identification of a novel C-type lectin receptor-ligand pair that is involved in T cell costimulation. The receptor, OCILRP2/Clr-g, is rapidly induced following T cell activation and maintained at a substantial level of up to 72 h. The ligand, NKRP1f, is predominantly expressed on dendritic cells (DC). The soluble OCILRP2-Ig blocking protein significantly suppresses specific antigen-stimulated T cell proliferation as well as IL-2 secretion both in vitro and in vivo; conversely, NKRP1f-expressing antigen presenting cells (APC) enhance B7.1/CD28-mediated costimulation for T cell proliferation through interaction with OCILRP2/Clr-g. Our studies reveal a unique functional interaction between two C-type lectins, OCILRP2/Clr-g and NKRP1f, during APC-mediated T cell costimulation and suggest a role for C-type lectins in maintaining T cell response or memory in vivo."xsd:string
http://purl.uniprot.org/citations/15963483http://purl.org/dc/terms/identifier"doi:10.1016/j.cellimm.2005.04.021"xsd:string
http://purl.uniprot.org/citations/15963483http://purl.org/dc/terms/identifier"doi:10.1016/j.cellimm.2005.04.021"xsd:string
http://purl.uniprot.org/citations/15963483http://purl.uniprot.org/core/author"Ding Y."xsd:string
http://purl.uniprot.org/citations/15963483http://purl.uniprot.org/core/author"Ding Y."xsd:string
http://purl.uniprot.org/citations/15963483http://purl.uniprot.org/core/author"Cheng S."xsd:string
http://purl.uniprot.org/citations/15963483http://purl.uniprot.org/core/author"Cheng S."xsd:string
http://purl.uniprot.org/citations/15963483http://purl.uniprot.org/core/author"Tian W."xsd:string
http://purl.uniprot.org/citations/15963483http://purl.uniprot.org/core/author"Tian W."xsd:string
http://purl.uniprot.org/citations/15963483http://purl.uniprot.org/core/author"Liou H.-C."xsd:string
http://purl.uniprot.org/citations/15963483http://purl.uniprot.org/core/author"Liou H.-C."xsd:string
http://purl.uniprot.org/citations/15963483http://purl.uniprot.org/core/author"Roman C."xsd:string
http://purl.uniprot.org/citations/15963483http://purl.uniprot.org/core/author"Roman C."xsd:string
http://purl.uniprot.org/citations/15963483http://purl.uniprot.org/core/author"Lyddane C."xsd:string
http://purl.uniprot.org/citations/15963483http://purl.uniprot.org/core/author"Lyddane C."xsd:string
http://purl.uniprot.org/citations/15963483http://purl.uniprot.org/core/author"Nunez R."xsd:string
http://purl.uniprot.org/citations/15963483http://purl.uniprot.org/core/author"Nunez R."xsd:string
http://purl.uniprot.org/citations/15963483http://purl.uniprot.org/core/author"Tumang J."xsd:string
http://purl.uniprot.org/citations/15963483http://purl.uniprot.org/core/author"Tumang J."xsd:string
http://purl.uniprot.org/citations/15963483http://purl.uniprot.org/core/date"2005"xsd:gYear
http://purl.uniprot.org/citations/15963483http://purl.uniprot.org/core/date"2005"xsd:gYear
http://purl.uniprot.org/citations/15963483http://purl.uniprot.org/core/name"Cell. Immunol."xsd:string
http://purl.uniprot.org/citations/15963483http://purl.uniprot.org/core/name"Cell. Immunol."xsd:string