http://purl.uniprot.org/citations/15965232 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/15965232 | http://www.w3.org/2000/01/rdf-schema#comment | "The transcriptional co-activator p300 has been reported to regulate the tumor suppressor p53 and its ortholog p73. Here we describe a study showing that this coactivator also regulates the transcriptional function of p63. p300 bound to the N-terminal domain of p63gamma, and p63gamma bound to the N terminus of p300 in vitro and in cells. p300, but not its acetylase-defective mutant AT2, stimulated p63gamma-dependent transcription and induction of p21 in cells, consequently leading to G1 arrest. Inversely, the deltaN-p63gamma isoform as well as p300AT2 inhibited the induction of p21 by p63gamma. These results suggest that p300 regulates p63-dependent transcription of p21."xsd:string |
http://purl.uniprot.org/citations/15965232 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.m503352200"xsd:string |
http://purl.uniprot.org/citations/15965232 | http://purl.uniprot.org/core/author | "Jin Y."xsd:string |
http://purl.uniprot.org/citations/15965232 | http://purl.uniprot.org/core/author | "Lee H."xsd:string |
http://purl.uniprot.org/citations/15965232 | http://purl.uniprot.org/core/author | "Lu H."xsd:string |
http://purl.uniprot.org/citations/15965232 | http://purl.uniprot.org/core/author | "Zeng S."xsd:string |
http://purl.uniprot.org/citations/15965232 | http://purl.uniprot.org/core/author | "Stauffer D."xsd:string |
http://purl.uniprot.org/citations/15965232 | http://purl.uniprot.org/core/author | "Thayer M."xsd:string |
http://purl.uniprot.org/citations/15965232 | http://purl.uniprot.org/core/author | "MacPartlin M."xsd:string |
http://purl.uniprot.org/citations/15965232 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
http://purl.uniprot.org/citations/15965232 | http://purl.uniprot.org/core/name | "J Biol Chem"xsd:string |
http://purl.uniprot.org/citations/15965232 | http://purl.uniprot.org/core/pages | "30604-30610"xsd:string |
http://purl.uniprot.org/citations/15965232 | http://purl.uniprot.org/core/title | "p300 regulates p63 transcriptional activity."xsd:string |
http://purl.uniprot.org/citations/15965232 | http://purl.uniprot.org/core/volume | "280"xsd:string |
http://purl.uniprot.org/citations/15965232 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/15965232 |
http://purl.uniprot.org/citations/15965232 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/15965232 |
http://purl.uniprot.org/uniprot/#_A0A141PNN3-mappedCitation-15965232 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15965232 |
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http://purl.uniprot.org/uniprot/#_A0A7D5Y1P9-mappedCitation-15965232 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15965232 |
http://purl.uniprot.org/uniprot/#_A0A7D5Y2H4-mappedCitation-15965232 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15965232 |
http://purl.uniprot.org/uniprot/#_A0A7D5Y2L4-mappedCitation-15965232 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15965232 |