http://purl.uniprot.org/citations/15975580 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/15975580 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/15975580 | http://www.w3.org/2000/01/rdf-schema#comment | "In Drosophila, the tumor suppressor Scribble is localized at the septate junctions of epithelial cells. Its mammalian homologue, hScrib, is a basolateral protein likely associated to proteins of the cell-cell junctions. We report the direct interaction between hScrib and ZO-2, a junction-associated protein. This interaction relies on two PDZ domains of hScrib and on the C-terminal motif of ZO-2. Both proteins localise at cell-cell junctions of epithelial cells. A point mutation in the LRR of hScrib delocalises the protein from the plasma membrane and abrogates the interaction with ZO-2 but not with betaPIX. Tyrosine phosphorylation of hScrib does not impair the interaction with ZO-2. We show a direct link between two junctional proteins that are down-regulated during cancer progression."xsd:string |
http://purl.uniprot.org/citations/15975580 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2005.05.062"xsd:string |
http://purl.uniprot.org/citations/15975580 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2005.05.062"xsd:string |
http://purl.uniprot.org/citations/15975580 | http://purl.uniprot.org/core/author | "Borg J.-P."xsd:string |
http://purl.uniprot.org/citations/15975580 | http://purl.uniprot.org/core/author | "Borg J.-P."xsd:string |
http://purl.uniprot.org/citations/15975580 | http://purl.uniprot.org/core/author | "Audebert S."xsd:string |
http://purl.uniprot.org/citations/15975580 | http://purl.uniprot.org/core/author | "Audebert S."xsd:string |
http://purl.uniprot.org/citations/15975580 | http://purl.uniprot.org/core/author | "Navarro C."xsd:string |
http://purl.uniprot.org/citations/15975580 | http://purl.uniprot.org/core/author | "Navarro C."xsd:string |
http://purl.uniprot.org/citations/15975580 | http://purl.uniprot.org/core/author | "Santoni M.-J."xsd:string |
http://purl.uniprot.org/citations/15975580 | http://purl.uniprot.org/core/author | "Santoni M.-J."xsd:string |
http://purl.uniprot.org/citations/15975580 | http://purl.uniprot.org/core/author | "Metais J.-Y."xsd:string |
http://purl.uniprot.org/citations/15975580 | http://purl.uniprot.org/core/author | "Metais J.-Y."xsd:string |
http://purl.uniprot.org/citations/15975580 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
http://purl.uniprot.org/citations/15975580 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
http://purl.uniprot.org/citations/15975580 | http://purl.uniprot.org/core/name | "FEBS Lett."xsd:string |
http://purl.uniprot.org/citations/15975580 | http://purl.uniprot.org/core/name | "FEBS Lett."xsd:string |
http://purl.uniprot.org/citations/15975580 | http://purl.uniprot.org/core/pages | "3725-3730"xsd:string |
http://purl.uniprot.org/citations/15975580 | http://purl.uniprot.org/core/pages | "3725-3730"xsd:string |
http://purl.uniprot.org/citations/15975580 | http://purl.uniprot.org/core/title | "hScrib interacts with ZO-2 at the cell-cell junctions of epithelial cells."xsd:string |
http://purl.uniprot.org/citations/15975580 | http://purl.uniprot.org/core/title | "hScrib interacts with ZO-2 at the cell-cell junctions of epithelial cells."xsd:string |
http://purl.uniprot.org/citations/15975580 | http://purl.uniprot.org/core/volume | "579"xsd:string |
http://purl.uniprot.org/citations/15975580 | http://purl.uniprot.org/core/volume | "579"xsd:string |