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http://purl.uniprot.org/citations/15979823http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/15979823http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/15979823http://www.w3.org/2000/01/rdf-schema#comment"Gliotoxin is a secondary metabolite produced by several fungi including the opportunistic animal pathogen Aspergillus fumigatus. It is a member of the epipolythiodioxopiperazine (ETP) class of toxins characterised by a disulphide bridged cyclic dipeptide. A putative cluster of 12 genes involved in gliotoxin biosynthesis has been identified in A. fumigatus by a comparative genomics approach based on homology to genes from the sirodesmin (another ETP) biosynthetic gene cluster of Leptosphaeria maculans. The physical limits of the cluster in A. fumigatus have been defined by bioinformatics and by identifying the genes that are co-regulated and whose timing of expression correlates with the production of gliotoxin in culture."xsd:string
http://purl.uniprot.org/citations/15979823http://purl.org/dc/terms/identifier"doi:10.1016/j.femsle.2005.05.046"xsd:string
http://purl.uniprot.org/citations/15979823http://purl.org/dc/terms/identifier"doi:10.1016/j.femsle.2005.05.046"xsd:string
http://purl.uniprot.org/citations/15979823http://purl.uniprot.org/core/author"Gardiner D.M."xsd:string
http://purl.uniprot.org/citations/15979823http://purl.uniprot.org/core/author"Gardiner D.M."xsd:string
http://purl.uniprot.org/citations/15979823http://purl.uniprot.org/core/author"Howlett B.J."xsd:string
http://purl.uniprot.org/citations/15979823http://purl.uniprot.org/core/author"Howlett B.J."xsd:string
http://purl.uniprot.org/citations/15979823http://purl.uniprot.org/core/date"2005"xsd:gYear
http://purl.uniprot.org/citations/15979823http://purl.uniprot.org/core/date"2005"xsd:gYear
http://purl.uniprot.org/citations/15979823http://purl.uniprot.org/core/name"FEMS Microbiol. Lett."xsd:string
http://purl.uniprot.org/citations/15979823http://purl.uniprot.org/core/name"FEMS Microbiol. Lett."xsd:string
http://purl.uniprot.org/citations/15979823http://purl.uniprot.org/core/pages"241-248"xsd:string
http://purl.uniprot.org/citations/15979823http://purl.uniprot.org/core/pages"241-248"xsd:string
http://purl.uniprot.org/citations/15979823http://purl.uniprot.org/core/title"Bioinformatic and expression analysis of the putative gliotoxin biosynthetic gene cluster of Aspergillus fumigatus."xsd:string
http://purl.uniprot.org/citations/15979823http://purl.uniprot.org/core/title"Bioinformatic and expression analysis of the putative gliotoxin biosynthetic gene cluster of Aspergillus fumigatus."xsd:string
http://purl.uniprot.org/citations/15979823http://purl.uniprot.org/core/volume"248"xsd:string
http://purl.uniprot.org/citations/15979823http://purl.uniprot.org/core/volume"248"xsd:string
http://purl.uniprot.org/citations/15979823http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/15979823
http://purl.uniprot.org/citations/15979823http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/15979823
http://purl.uniprot.org/citations/15979823http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/15979823
http://purl.uniprot.org/citations/15979823http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/15979823
http://purl.uniprot.org/uniprot/E9R9Y3http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/15979823
http://purl.uniprot.org/uniprot/Q4WMJ9http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/15979823