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http://purl.uniprot.org/citations/15980434http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/15980434http://www.w3.org/2000/01/rdf-schema#comment"The Kruppel-like factor KLF2 was recently identified as a novel regulator of endothelial pro-inflammatory and pro-thrombotic function. Here it is shown that overexpression of KLF2 potently inhibits vascular permeability factor/vascular endothelial growth factor (VEGF-A)-mediated angiogenesis and tissue edema in the nude ear mouse model of angiogenesis. In vitro, KLF2 expression retards VEGF-mediated calcium flux, proliferation and induction of pro-inflammatory factors in endothelial cells. This effect is due to a potent inhibition of VEGFR2/KDR expression and promoter activity. These observations identify KLF2 as a regulator of VEGFR2/KDR and provide a foundation for novel approaches to regulate angiogenesis."xsd:string
http://purl.uniprot.org/citations/15980434http://purl.org/dc/terms/identifier"doi:10.1074/jbc.c500200200"xsd:string
http://purl.uniprot.org/citations/15980434http://purl.uniprot.org/core/author"Lin Z."xsd:string
http://purl.uniprot.org/citations/15980434http://purl.uniprot.org/core/author"Wang P."xsd:string
http://purl.uniprot.org/citations/15980434http://purl.uniprot.org/core/author"Mukhopadhyay D."xsd:string
http://purl.uniprot.org/citations/15980434http://purl.uniprot.org/core/author"Mir S."xsd:string
http://purl.uniprot.org/citations/15980434http://purl.uniprot.org/core/author"Mukherjee P."xsd:string
http://purl.uniprot.org/citations/15980434http://purl.uniprot.org/core/author"Jain M.K."xsd:string
http://purl.uniprot.org/citations/15980434http://purl.uniprot.org/core/author"Bhattacharya R."xsd:string
http://purl.uniprot.org/citations/15980434http://purl.uniprot.org/core/author"Hamik A."xsd:string
http://purl.uniprot.org/citations/15980434http://purl.uniprot.org/core/author"Senbanerjee S."xsd:string
http://purl.uniprot.org/citations/15980434http://purl.uniprot.org/core/date"2005"xsd:gYear
http://purl.uniprot.org/citations/15980434http://purl.uniprot.org/core/name"J Biol Chem"xsd:string
http://purl.uniprot.org/citations/15980434http://purl.uniprot.org/core/pages"28848-28851"xsd:string
http://purl.uniprot.org/citations/15980434http://purl.uniprot.org/core/title"Inhibition of vascular permeability factor/vascular endothelial growth factor-mediated angiogenesis by the Kruppel-like factor KLF2."xsd:string
http://purl.uniprot.org/citations/15980434http://purl.uniprot.org/core/volume"280"xsd:string
http://purl.uniprot.org/citations/15980434http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/15980434
http://purl.uniprot.org/citations/15980434http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/15980434
http://purl.uniprot.org/uniprot/#_A0A0U2WZU8-mappedCitation-15980434http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15980434
http://purl.uniprot.org/uniprot/#_A0A0U2X4C8-mappedCitation-15980434http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15980434
http://purl.uniprot.org/uniprot/#_A0A0H4A777-mappedCitation-15980434http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15980434
http://purl.uniprot.org/uniprot/#_A0A0H4A7S0-mappedCitation-15980434http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15980434
http://purl.uniprot.org/uniprot/#_A0A0H4A7S4-mappedCitation-15980434http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15980434
http://purl.uniprot.org/uniprot/#_A0A0H4ADZ1-mappedCitation-15980434http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15980434