http://purl.uniprot.org/citations/15986473 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/15986473 | http://www.w3.org/2000/01/rdf-schema#comment | "In Caenorhabditis elegans, lack of the conserved germline RNA helicase CGH-1 causes infertility and excessive levels of physiological germline apoptosis, a process that normally claims about half of all developing oocytes. In yeast the CGH-1 ortholog is a key component of degradative "processing (P) bodies," which may share some properties with germline protein-RNA complexes such as P granules. During oogenesis CGH-1 associates with P granules, but also accumulates to high levels in additional cytoplasmic particles. Here we show that appropriate levels and localization of CGH-1 depends on some P granule components and on mechanisms that establish meiotic development. At the same time, germ cell death is not increased by various abnormalities in P granules or meiosis. We conclude that in developing oocytes CGH-1 particles accumulate specifically in response to meiotic development and have distinct functions from P granules, and may be dynamic protein-mRNA structures."xsd:string |
http://purl.uniprot.org/citations/15986473 | http://purl.org/dc/terms/identifier | "doi:10.1002/gene.20136"xsd:string |
http://purl.uniprot.org/citations/15986473 | http://purl.uniprot.org/core/author | "Navarro R.E."xsd:string |
http://purl.uniprot.org/citations/15986473 | http://purl.uniprot.org/core/author | "Blackwell T.K."xsd:string |
http://purl.uniprot.org/citations/15986473 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
http://purl.uniprot.org/citations/15986473 | http://purl.uniprot.org/core/name | "Genesis"xsd:string |
http://purl.uniprot.org/citations/15986473 | http://purl.uniprot.org/core/pages | "172-180"xsd:string |
http://purl.uniprot.org/citations/15986473 | http://purl.uniprot.org/core/title | "Requirement for P granules and meiosis for accumulation of the germline RNA helicase CGH-1."xsd:string |
http://purl.uniprot.org/citations/15986473 | http://purl.uniprot.org/core/volume | "42"xsd:string |
http://purl.uniprot.org/citations/15986473 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/15986473 |
http://purl.uniprot.org/citations/15986473 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/15986473 |
http://purl.uniprot.org/uniprot/#_P34689-mappedCitation-15986473 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15986473 |
http://purl.uniprot.org/uniprot/#_Q966L9-mappedCitation-15986473 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15986473 |
http://purl.uniprot.org/uniprot/#_Q95YF3-mappedCitation-15986473 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15986473 |
http://purl.uniprot.org/uniprot/P34689 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/15986473 |
http://purl.uniprot.org/uniprot/Q95YF3 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/15986473 |
http://purl.uniprot.org/uniprot/Q966L9 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/15986473 |