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http://purl.uniprot.org/citations/15986473http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/15986473http://www.w3.org/2000/01/rdf-schema#comment"In Caenorhabditis elegans, lack of the conserved germline RNA helicase CGH-1 causes infertility and excessive levels of physiological germline apoptosis, a process that normally claims about half of all developing oocytes. In yeast the CGH-1 ortholog is a key component of degradative "processing (P) bodies," which may share some properties with germline protein-RNA complexes such as P granules. During oogenesis CGH-1 associates with P granules, but also accumulates to high levels in additional cytoplasmic particles. Here we show that appropriate levels and localization of CGH-1 depends on some P granule components and on mechanisms that establish meiotic development. At the same time, germ cell death is not increased by various abnormalities in P granules or meiosis. We conclude that in developing oocytes CGH-1 particles accumulate specifically in response to meiotic development and have distinct functions from P granules, and may be dynamic protein-mRNA structures."xsd:string
http://purl.uniprot.org/citations/15986473http://purl.org/dc/terms/identifier"doi:10.1002/gene.20136"xsd:string
http://purl.uniprot.org/citations/15986473http://purl.uniprot.org/core/author"Navarro R.E."xsd:string
http://purl.uniprot.org/citations/15986473http://purl.uniprot.org/core/author"Blackwell T.K."xsd:string
http://purl.uniprot.org/citations/15986473http://purl.uniprot.org/core/date"2005"xsd:gYear
http://purl.uniprot.org/citations/15986473http://purl.uniprot.org/core/name"Genesis"xsd:string
http://purl.uniprot.org/citations/15986473http://purl.uniprot.org/core/pages"172-180"xsd:string
http://purl.uniprot.org/citations/15986473http://purl.uniprot.org/core/title"Requirement for P granules and meiosis for accumulation of the germline RNA helicase CGH-1."xsd:string
http://purl.uniprot.org/citations/15986473http://purl.uniprot.org/core/volume"42"xsd:string
http://purl.uniprot.org/citations/15986473http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/15986473
http://purl.uniprot.org/citations/15986473http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/15986473
http://purl.uniprot.org/uniprot/#_P34689-mappedCitation-15986473http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15986473
http://purl.uniprot.org/uniprot/#_Q966L9-mappedCitation-15986473http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15986473
http://purl.uniprot.org/uniprot/#_Q95YF3-mappedCitation-15986473http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15986473
http://purl.uniprot.org/uniprot/P34689http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/15986473
http://purl.uniprot.org/uniprot/Q95YF3http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/15986473
http://purl.uniprot.org/uniprot/Q966L9http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/15986473