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http://purl.uniprot.org/citations/15987637http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/15987637http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/15987637http://www.w3.org/2000/01/rdf-schema#comment"Calmodulin (CaM), a key Ca(2+) sensor in eukaryotes, regulates diverse cellular processes by interacting with many proteins. To identify Ca(2+)/CaM-mediated signaling components, we screened an Arabidopsis expression library with horseradish peroxidase-conjugated Arabidopsis calmodulin2 (AtCaM2) and isolated a homolog of the UBP6 deubiquitinating enzyme family (AtUBP6) containing a Ca(2+)-dependent CaM-binding domain (CaMBD). The CaM-binding activity of the AtUBP6 CaMBD was confirmed by CaM mobility shift assay, phosphodiesterase competition assay and site-directed mutagenesis. Furthermore, expression of AtUBP6 restored canavanine resistance to the Deltaubp6 yeast mutant. This is the first demonstration that Ca(2+) signaling via CaM is involved in ubiquitin-mediated protein degradation and/or stabilization in plants."xsd:string
http://purl.uniprot.org/citations/15987637http://purl.org/dc/terms/identifier"doi:10.1016/j.febslet.2005.05.080"xsd:string
http://purl.uniprot.org/citations/15987637http://purl.org/dc/terms/identifier"doi:10.1016/j.febslet.2005.05.080"xsd:string
http://purl.uniprot.org/citations/15987637http://purl.uniprot.org/core/author"Cho M.J."xsd:string
http://purl.uniprot.org/citations/15987637http://purl.uniprot.org/core/author"Cho M.J."xsd:string
http://purl.uniprot.org/citations/15987637http://purl.uniprot.org/core/author"Lee S.M."xsd:string
http://purl.uniprot.org/citations/15987637http://purl.uniprot.org/core/author"Lee S.M."xsd:string
http://purl.uniprot.org/citations/15987637http://purl.uniprot.org/core/author"Lim C.O."xsd:string
http://purl.uniprot.org/citations/15987637http://purl.uniprot.org/core/author"Lim C.O."xsd:string
http://purl.uniprot.org/citations/15987637http://purl.uniprot.org/core/author"Moon B.C."xsd:string
http://purl.uniprot.org/citations/15987637http://purl.uniprot.org/core/author"Moon B.C."xsd:string
http://purl.uniprot.org/citations/15987637http://purl.uniprot.org/core/author"Kang Y.H."xsd:string
http://purl.uniprot.org/citations/15987637http://purl.uniprot.org/core/author"Kang Y.H."xsd:string
http://purl.uniprot.org/citations/15987637http://purl.uniprot.org/core/author"Kim M.C."xsd:string
http://purl.uniprot.org/citations/15987637http://purl.uniprot.org/core/author"Kim M.C."xsd:string
http://purl.uniprot.org/citations/15987637http://purl.uniprot.org/core/author"Chung W.S."xsd:string
http://purl.uniprot.org/citations/15987637http://purl.uniprot.org/core/author"Chung W.S."xsd:string
http://purl.uniprot.org/citations/15987637http://purl.uniprot.org/core/author"Choi M.S."xsd:string
http://purl.uniprot.org/citations/15987637http://purl.uniprot.org/core/author"Choi M.S."xsd:string
http://purl.uniprot.org/citations/15987637http://purl.uniprot.org/core/author"Koo S.C."xsd:string
http://purl.uniprot.org/citations/15987637http://purl.uniprot.org/core/author"Koo S.C."xsd:string
http://purl.uniprot.org/citations/15987637http://purl.uniprot.org/core/author"Yoo J.H."xsd:string
http://purl.uniprot.org/citations/15987637http://purl.uniprot.org/core/author"Yoo J.H."xsd:string