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http://purl.uniprot.org/citations/15992545http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/15992545http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/15992545http://www.w3.org/2000/01/rdf-schema#comment"The plant hormone auxin has been implicated in virtually every aspect of plant growth and development. Auxin acts by promoting the degradation of transcriptional regulators called Aux/IAA proteins. Aux/IAA degradation requires TIR1, an F box protein that has been shown to function as an auxin receptor. However, loss of TIR1 has a modest effect on auxin response and plant development. Here we show that three additional F box proteins, called AFB1, 2, and 3, also regulate auxin response. Like TIR1, these proteins interact with the Aux/IAA proteins in an auxin-dependent manner. Plants that are deficient in all four proteins are auxin insensitive and exhibit a severe embryonic phenotype similar to the mp/arf5 and bdl/iaa12 mutants. Correspondingly, all TIR1/AFB proteins interact with BDL, and BDL is stabilized in triple mutant plants. Our results indicate that TIR1 and the AFB proteins collectively mediate auxin responses throughout plant development."xsd:string
http://purl.uniprot.org/citations/15992545http://purl.org/dc/terms/identifier"doi:10.1016/j.devcel.2005.05.014"xsd:string
http://purl.uniprot.org/citations/15992545http://purl.org/dc/terms/identifier"doi:10.1016/j.devcel.2005.05.014"xsd:string
http://purl.uniprot.org/citations/15992545http://purl.uniprot.org/core/author"Yamada M."xsd:string
http://purl.uniprot.org/citations/15992545http://purl.uniprot.org/core/author"Yamada M."xsd:string
http://purl.uniprot.org/citations/15992545http://purl.uniprot.org/core/author"Juergens G."xsd:string
http://purl.uniprot.org/citations/15992545http://purl.uniprot.org/core/author"Juergens G."xsd:string
http://purl.uniprot.org/citations/15992545http://purl.uniprot.org/core/author"Estelle M."xsd:string
http://purl.uniprot.org/citations/15992545http://purl.uniprot.org/core/author"Estelle M."xsd:string
http://purl.uniprot.org/citations/15992545http://purl.uniprot.org/core/author"Lechner E."xsd:string
http://purl.uniprot.org/citations/15992545http://purl.uniprot.org/core/author"Lechner E."xsd:string
http://purl.uniprot.org/citations/15992545http://purl.uniprot.org/core/author"Dharmasiri N."xsd:string
http://purl.uniprot.org/citations/15992545http://purl.uniprot.org/core/author"Dharmasiri N."xsd:string
http://purl.uniprot.org/citations/15992545http://purl.uniprot.org/core/author"Dharmasiri S."xsd:string
http://purl.uniprot.org/citations/15992545http://purl.uniprot.org/core/author"Dharmasiri S."xsd:string
http://purl.uniprot.org/citations/15992545http://purl.uniprot.org/core/author"Ehrismann J.S."xsd:string
http://purl.uniprot.org/citations/15992545http://purl.uniprot.org/core/author"Ehrismann J.S."xsd:string
http://purl.uniprot.org/citations/15992545http://purl.uniprot.org/core/author"Hobbie L."xsd:string
http://purl.uniprot.org/citations/15992545http://purl.uniprot.org/core/author"Hobbie L."xsd:string
http://purl.uniprot.org/citations/15992545http://purl.uniprot.org/core/author"Weijers D."xsd:string
http://purl.uniprot.org/citations/15992545http://purl.uniprot.org/core/author"Weijers D."xsd:string
http://purl.uniprot.org/citations/15992545http://purl.uniprot.org/core/date"2005"xsd:gYear
http://purl.uniprot.org/citations/15992545http://purl.uniprot.org/core/date"2005"xsd:gYear