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http://purl.uniprot.org/citations/15998451http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/15998451http://www.w3.org/2000/01/rdf-schema#comment"As genome-scale measurements lead to increasingly complex models of gene regulation, systematic approaches are needed to validate and refine these models. Towards this goal, we describe an automated procedure for prioritizing genetic perturbations in order to discriminate optimally between alternative models of a gene-regulatory network. Using this procedure, we evaluate 38 candidate regulatory networks in yeast and perform four high-priority gene knockout experiments. The refined networks support previously unknown regulatory mechanisms downstream of SOK2 and SWI4."xsd:string
http://purl.uniprot.org/citations/15998451http://purl.org/dc/terms/identifier"doi:10.1186/gb-2005-6-7-r62"xsd:string
http://purl.uniprot.org/citations/15998451http://purl.uniprot.org/core/author"Ideker T."xsd:string
http://purl.uniprot.org/citations/15998451http://purl.uniprot.org/core/author"Workman C."xsd:string
http://purl.uniprot.org/citations/15998451http://purl.uniprot.org/core/author"Jaakkola T."xsd:string
http://purl.uniprot.org/citations/15998451http://purl.uniprot.org/core/author"Mak H.C."xsd:string
http://purl.uniprot.org/citations/15998451http://purl.uniprot.org/core/author"McCuine S."xsd:string
http://purl.uniprot.org/citations/15998451http://purl.uniprot.org/core/author"Yeang C.H."xsd:string
http://purl.uniprot.org/citations/15998451http://purl.uniprot.org/core/date"2005"xsd:gYear
http://purl.uniprot.org/citations/15998451http://purl.uniprot.org/core/name"Genome Biol"xsd:string
http://purl.uniprot.org/citations/15998451http://purl.uniprot.org/core/pages"R62"xsd:string
http://purl.uniprot.org/citations/15998451http://purl.uniprot.org/core/title"Validation and refinement of gene-regulatory pathways on a network of physical interactions."xsd:string
http://purl.uniprot.org/citations/15998451http://purl.uniprot.org/core/volume"6"xsd:string
http://purl.uniprot.org/citations/15998451http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/15998451
http://purl.uniprot.org/citations/15998451http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/15998451
http://purl.uniprot.org/uniprot/#_P14064-mappedCitation-15998451http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15998451
http://purl.uniprot.org/uniprot/#_P33749-mappedCitation-15998451http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15998451
http://purl.uniprot.org/uniprot/#_P53438-mappedCitation-15998451http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15998451
http://purl.uniprot.org/uniprot/#_Q03935-mappedCitation-15998451http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15998451
http://purl.uniprot.org/uniprot/P14064http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/15998451
http://purl.uniprot.org/uniprot/P33749http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/15998451
http://purl.uniprot.org/uniprot/Q03935http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/15998451
http://purl.uniprot.org/uniprot/P53438http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/15998451