| http://purl.uniprot.org/citations/16002694 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16002694 | http://www.w3.org/2000/01/rdf-schema#comment | "The forkhead transcription factor Foxj1 inhibits spontaneous autoimmunity, in part by antagonizing NF-kappaB activation in T cells. We demonstrate here that Foxj1 also inhibits humoral immune responses intrinsically in B cells; Foxj1 deficiency in B cells results in spontaneous and accentuated germinal center formation, associated with the development of pathogenic autoantibodies and accentuated responses to immunizations-all reflecting excessive activity of NF-kappaB and its target gene IL-6, and correlating with a requirement for Foxj1 to regulate the inhibitory NF-kappaB component IkappaBbeta. Thus, Foxj1 restrains B cell activation and the maturation of humoral responses, demonstrating a critical role for at least this forkhead transcription factor in the regulation of B lymphocyte homeostasis."xsd:string |
| http://purl.uniprot.org/citations/16002694 | http://purl.org/dc/terms/identifier | "doi:10.4049/jimmunol.175.2.951"xsd:string |
| http://purl.uniprot.org/citations/16002694 | http://purl.uniprot.org/core/author | "Lin L."xsd:string |
| http://purl.uniprot.org/citations/16002694 | http://purl.uniprot.org/core/author | "Peng S.L."xsd:string |
| http://purl.uniprot.org/citations/16002694 | http://purl.uniprot.org/core/author | "Brody S.L."xsd:string |
| http://purl.uniprot.org/citations/16002694 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
| http://purl.uniprot.org/citations/16002694 | http://purl.uniprot.org/core/name | "J Immunol"xsd:string |
| http://purl.uniprot.org/citations/16002694 | http://purl.uniprot.org/core/pages | "951-958"xsd:string |
| http://purl.uniprot.org/citations/16002694 | http://purl.uniprot.org/core/title | "Restraint of B cell activation by Foxj1-mediated antagonism of NF-kappa B and IL-6."xsd:string |
| http://purl.uniprot.org/citations/16002694 | http://purl.uniprot.org/core/volume | "175"xsd:string |
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