http://purl.uniprot.org/citations/16005964 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/16005964 | http://www.w3.org/2000/01/rdf-schema#comment | "CCAAT/enhancer binding proteins (C/EBPs) are a family of transcription factors that have been implicated in diverse cellular functions such as cellular differentiation and proliferation, and inflammatory processes. C/EBPzeta, also known as GADD153, CHOP10, and DDIT3 has been found associated with the development of myxoid liposarcoma and the progression of melanoma. To investigate the correlation of C/EBPzeta transcript levels with the development of leukemia, samples from 187 patients with myelodysplastic syndrome (MDS), acute myeloid leukemia (AML), and chronic myeloid leukemia (CML) were examined for C/EBPzeta mRNA using real-time quantitative PCR (RQ-PCR). RQ-PCR analysis demonstrated the median levels of C/EBPzeta were significantly decreased in MDS, AML, and CML patients compared with normal controls (1.40, 0.96, 2.60 versus 14.69, P<0.0001). Significant differences were also observed between patients with CML and with AML or MDS. These results suggest that the insufficient dosage of C/EBPzeta might be involved in the development of leukemia."xsd:string |
http://purl.uniprot.org/citations/16005964 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.leukres.2005.05.020"xsd:string |
http://purl.uniprot.org/citations/16005964 | http://purl.uniprot.org/core/author | "Chen Z."xsd:string |
http://purl.uniprot.org/citations/16005964 | http://purl.uniprot.org/core/author | "Lin J."xsd:string |
http://purl.uniprot.org/citations/16005964 | http://purl.uniprot.org/core/author | "Wang W."xsd:string |
http://purl.uniprot.org/citations/16005964 | http://purl.uniprot.org/core/author | "Qian J."xsd:string |
http://purl.uniprot.org/citations/16005964 | http://purl.uniprot.org/core/author | "Cen J."xsd:string |
http://purl.uniprot.org/citations/16005964 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
http://purl.uniprot.org/citations/16005964 | http://purl.uniprot.org/core/name | "Leuk Res"xsd:string |
http://purl.uniprot.org/citations/16005964 | http://purl.uniprot.org/core/pages | "1435-1441"xsd:string |
http://purl.uniprot.org/citations/16005964 | http://purl.uniprot.org/core/title | "Decreased expression of CCAAT/enhancer binding protein zeta (C/EBPzeta) in patients with different myeloid diseases."xsd:string |
http://purl.uniprot.org/citations/16005964 | http://purl.uniprot.org/core/volume | "29"xsd:string |
http://purl.uniprot.org/citations/16005964 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/16005964 |
http://purl.uniprot.org/citations/16005964 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/16005964 |
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http://purl.uniprot.org/uniprot/#_P0DPQ6-mappedCitation-16005964 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16005964 |
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http://purl.uniprot.org/uniprot/P35638 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/16005964 |
http://purl.uniprot.org/uniprot/Q53YD1 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/16005964 |
http://purl.uniprot.org/uniprot/P0DPQ6 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/16005964 |