| http://purl.uniprot.org/citations/16011982 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16011982 | http://www.w3.org/2000/01/rdf-schema#comment | "Many authors have recently found a positive correlation between Helicobacter pylori infection and idiopathic thrombocytopenic purpura (ITP), the most common autoimmune hematological disorder. In order to clarify the pathogenic mechanism of H. pylori-associated ITP, we have investigated 52 consecutive ITP adult patients for Helicobacter pylori infection, B- and T-cell clonality and HLA class II alleles. Thirty-four ITP patients (65.4%) were infected by H. pylori and bacterium eradication was accompanied by a long-term platelet response in 17 (53.1%) of them. A B-cell clonality was found in three patients (5.8%, two patients H. pylori-negative and one patient H. pylori-positive). The ITP patients with H. pylori infection showed a HLA-DRB1*11, *14 and -DQB1*03 frequencies significantly higher and a -DRB1*03 frequency significantly lower than in H. pylori-negative patients. Moreover, an HLA-DQB1*03 pattern was associated with a higher probability of platelet response to eradication treatment. If our study documents the efficacy of eradication treatment in H. pylori-infected ITP patients, it may also help to identify different subgroups of ITP patients with probably different pathogeneses of thrombocytopenia and, finally, different responses to eradication treatment."xsd:string |
| http://purl.uniprot.org/citations/16011982 | http://purl.org/dc/terms/identifier | "doi:10.1080/09537100400028685"xsd:string |
| http://purl.uniprot.org/citations/16011982 | http://purl.uniprot.org/core/author | "Federici F."xsd:string |
| http://purl.uniprot.org/citations/16011982 | http://purl.uniprot.org/core/author | "Franchini M."xsd:string |
| http://purl.uniprot.org/citations/16011982 | http://purl.uniprot.org/core/author | "Arena S."xsd:string |
| http://purl.uniprot.org/citations/16011982 | http://purl.uniprot.org/core/author | "Guizzardi E."xsd:string |
| http://purl.uniprot.org/citations/16011982 | http://purl.uniprot.org/core/author | "De Matteis G."xsd:string |
| http://purl.uniprot.org/citations/16011982 | http://purl.uniprot.org/core/author | "Solero P."xsd:string |
| http://purl.uniprot.org/citations/16011982 | http://purl.uniprot.org/core/author | "Veneri D."xsd:string |
| http://purl.uniprot.org/citations/16011982 | http://purl.uniprot.org/core/author | "Gaio M."xsd:string |
| http://purl.uniprot.org/citations/16011982 | http://purl.uniprot.org/core/author | "Pontiero P."xsd:string |
| http://purl.uniprot.org/citations/16011982 | http://purl.uniprot.org/core/author | "Ricetti M.M."xsd:string |
| http://purl.uniprot.org/citations/16011982 | http://purl.uniprot.org/core/author | "Zanuso C."xsd:string |
| http://purl.uniprot.org/citations/16011982 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
| http://purl.uniprot.org/citations/16011982 | http://purl.uniprot.org/core/name | "Platelets"xsd:string |
| http://purl.uniprot.org/citations/16011982 | http://purl.uniprot.org/core/pages | "307-311"xsd:string |
| http://purl.uniprot.org/citations/16011982 | http://purl.uniprot.org/core/title | "Analysis of B- and T-cell clonality and HLA class II alleles in patients with idiopathic thrombocytopenic purpura: correlation with Helicobacter pylori infection and response to eradication treatment."xsd:string |
| http://purl.uniprot.org/citations/16011982 | http://purl.uniprot.org/core/volume | "16"xsd:string |
| http://purl.uniprot.org/citations/16011982 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/16011982 |
| http://purl.uniprot.org/citations/16011982 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/16011982 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C3H3-mappedCitation-16011982 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16011982 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C3I1-mappedCitation-16011982 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16011982 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C3I5-mappedCitation-16011982 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16011982 |
| http://purl.uniprot.org/uniprot/#_A0A0E3DC97-mappedCitation-16011982 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16011982 |