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http://purl.uniprot.org/citations/16019679http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/16019679http://www.w3.org/2000/01/rdf-schema#comment"

Purpose

To investigate the immunogenetic background of human T-cell lymphotropic virus type 1 (HTLV-1)-associated uveitis (HAU) that presents immune-mediated reactive changes in the uvea.

Methods

HLA class I and class II genes were studied in 51 patients with HAU, 192 asymptomatic HTLV-1 carriers, and 266 HTLV-1-seronegative controls using a high-resolution method of HLA DNA typing. The HLA alleles of HAU were compared with those of HTLV-1 carriers and healthy controls.

Results

We identified 62 distinct alleles of HLA-A, HLA-Cw, and HLA-B and 49 distinct alleles of HLA-DRB1 and HLA-DQB1 in patients with HAU, asymptomatic HTLV-1 carriers, and healthy controls. The relative frequencies of these HLA alleles did not differ among the three groups.

Conclusion

The results suggest that HLA class I and class II genes do not contribute to susceptibility to HAU."xsd:string
http://purl.uniprot.org/citations/16019679http://purl.org/dc/terms/identifier"doi:10.1080/09273940590928670"xsd:string
http://purl.uniprot.org/citations/16019679http://purl.uniprot.org/core/author"Nakao K."xsd:string
http://purl.uniprot.org/citations/16019679http://purl.uniprot.org/core/author"Sakamoto T."xsd:string
http://purl.uniprot.org/citations/16019679http://purl.uniprot.org/core/author"Ohba N."xsd:string
http://purl.uniprot.org/citations/16019679http://purl.uniprot.org/core/author"Sonoda S."xsd:string
http://purl.uniprot.org/citations/16019679http://purl.uniprot.org/core/author"Yashiki S."xsd:string
http://purl.uniprot.org/citations/16019679http://purl.uniprot.org/core/author"Kaminagayoshi T."xsd:string
http://purl.uniprot.org/citations/16019679http://purl.uniprot.org/core/date"2005"xsd:gYear
http://purl.uniprot.org/citations/16019679http://purl.uniprot.org/core/name"Ocul Immunol Inflamm"xsd:string
http://purl.uniprot.org/citations/16019679http://purl.uniprot.org/core/pages"199-204"xsd:string
http://purl.uniprot.org/citations/16019679http://purl.uniprot.org/core/title"Analysis of HLA class I and class II gene polymorphisms in Japanese patients with human T-cell lymphotropic virus type 1-associated uveitis."xsd:string
http://purl.uniprot.org/citations/16019679http://purl.uniprot.org/core/volume"13"xsd:string
http://purl.uniprot.org/citations/16019679http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/16019679
http://purl.uniprot.org/citations/16019679http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/16019679
http://purl.uniprot.org/uniprot/#_A0A0A7C3H3-mappedCitation-16019679http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/16019679
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http://purl.uniprot.org/uniprot/#_A0A0A7C545-mappedCitation-16019679http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/16019679
http://purl.uniprot.org/uniprot/#_A0A0A7C548-mappedCitation-16019679http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/16019679
http://purl.uniprot.org/uniprot/#_A0A0A7C549-mappedCitation-16019679http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/16019679
http://purl.uniprot.org/uniprot/#_A0A0A7C550-mappedCitation-16019679http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/16019679
http://purl.uniprot.org/uniprot/#_A0A0A7C551-mappedCitation-16019679http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/16019679
http://purl.uniprot.org/uniprot/#_A0A0A7C552-mappedCitation-16019679http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/16019679
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