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| http://purl.uniprot.org/citations/16020693 | http://www.w3.org/2000/01/rdf-schema#comment | "Most studies of host-pathogen interactions have focused on pathogen-specific virulence determinants. Here, we report a genome-wide RNA interference screen to identify host factors required for intracellular bacterial pathogenesis. Using Drosophila cells and the cytosolic pathogen Listeria monocytogenes, we identified 305 double-stranded RNAs targeting a wide range of cellular functions that altered L. monocytogenes infection. Comparison to a similar screen with Mycobacterium fortuitum, a vacuolar pathogen, identified host factors that may play a general role in intracellular pathogenesis and factors that specifically affect access to the cytosol by L. monocytogenes."xsd:string |
| http://purl.uniprot.org/citations/16020693 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.1116008"xsd:string |
| http://purl.uniprot.org/citations/16020693 | http://purl.uniprot.org/core/author | "Perrimon N."xsd:string |
| http://purl.uniprot.org/citations/16020693 | http://purl.uniprot.org/core/author | "Rubin E.J."xsd:string |
| http://purl.uniprot.org/citations/16020693 | http://purl.uniprot.org/core/author | "Higgins D.E."xsd:string |
| http://purl.uniprot.org/citations/16020693 | http://purl.uniprot.org/core/author | "Philips J.A."xsd:string |
| http://purl.uniprot.org/citations/16020693 | http://purl.uniprot.org/core/author | "Burrack L.S."xsd:string |
| http://purl.uniprot.org/citations/16020693 | http://purl.uniprot.org/core/author | "Agaisse H."xsd:string |
| http://purl.uniprot.org/citations/16020693 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
| http://purl.uniprot.org/citations/16020693 | http://purl.uniprot.org/core/name | "Science"xsd:string |
| http://purl.uniprot.org/citations/16020693 | http://purl.uniprot.org/core/pages | "1248-1251"xsd:string |
| http://purl.uniprot.org/citations/16020693 | http://purl.uniprot.org/core/title | "Genome-wide RNAi screen for host factors required for intracellular bacterial infection."xsd:string |
| http://purl.uniprot.org/citations/16020693 | http://purl.uniprot.org/core/volume | "309"xsd:string |
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