http://purl.uniprot.org/citations/16020694 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/16020694 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/16020694 | http://www.w3.org/2000/01/rdf-schema#comment | "Certain pathogens, such as Mycobacterium tuberculosis, survive within the hostile intracellular environment of a macrophage. To identify host factors required for mycobacterial entry and survival within macrophages, we performed a genomewide RNA interference screen in Drosophila macrophage-like cells, using Mycobacterium fortuitum. We identified factors required for general phagocytosis, as well as those needed specifically for mycobacterial infection. One specific factor, Peste (Pes), is a CD36 family member required for uptake of mycobacteria, but not Escherichia coli or Staphylococcus aureus. Moreover, mammalian class B scavenger receptors (SRs) conferred uptake of bacteria into nonphagocytic cells, with SR-BI and SR-BII uniquely mediating uptake of M. fortuitum, which suggests a conserved role for class B SRs in pattern recognition and innate immunity."xsd:string |
http://purl.uniprot.org/citations/16020694 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.1116006"xsd:string |
http://purl.uniprot.org/citations/16020694 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.1116006"xsd:string |
http://purl.uniprot.org/citations/16020694 | http://purl.uniprot.org/core/author | "Perrimon N."xsd:string |
http://purl.uniprot.org/citations/16020694 | http://purl.uniprot.org/core/author | "Perrimon N."xsd:string |
http://purl.uniprot.org/citations/16020694 | http://purl.uniprot.org/core/author | "Rubin E.J."xsd:string |
http://purl.uniprot.org/citations/16020694 | http://purl.uniprot.org/core/author | "Rubin E.J."xsd:string |
http://purl.uniprot.org/citations/16020694 | http://purl.uniprot.org/core/author | "Philips J.A."xsd:string |
http://purl.uniprot.org/citations/16020694 | http://purl.uniprot.org/core/author | "Philips J.A."xsd:string |
http://purl.uniprot.org/citations/16020694 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
http://purl.uniprot.org/citations/16020694 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
http://purl.uniprot.org/citations/16020694 | http://purl.uniprot.org/core/name | "Science"xsd:string |
http://purl.uniprot.org/citations/16020694 | http://purl.uniprot.org/core/name | "Science"xsd:string |
http://purl.uniprot.org/citations/16020694 | http://purl.uniprot.org/core/pages | "1251-1253"xsd:string |
http://purl.uniprot.org/citations/16020694 | http://purl.uniprot.org/core/pages | "1251-1253"xsd:string |
http://purl.uniprot.org/citations/16020694 | http://purl.uniprot.org/core/title | "Drosophila RNAi screen reveals CD36 family member required for mycobacterial infection."xsd:string |
http://purl.uniprot.org/citations/16020694 | http://purl.uniprot.org/core/title | "Drosophila RNAi screen reveals CD36 family member required for mycobacterial infection."xsd:string |
http://purl.uniprot.org/citations/16020694 | http://purl.uniprot.org/core/volume | "309"xsd:string |
http://purl.uniprot.org/citations/16020694 | http://purl.uniprot.org/core/volume | "309"xsd:string |
http://purl.uniprot.org/citations/16020694 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/16020694 |
http://purl.uniprot.org/citations/16020694 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/16020694 |
http://purl.uniprot.org/citations/16020694 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/16020694 |
http://purl.uniprot.org/citations/16020694 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/16020694 |