| http://purl.uniprot.org/citations/16020728 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16020728 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16020728 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16020728 | http://www.w3.org/2000/01/rdf-schema#comment | "Leishmania species cause a spectrum of human diseases in tropical and subtropical regions of the world. We have sequenced the 36 chromosomes of the 32.8-megabase haploid genome of Leishmania major (Friedlin strain) and predict 911 RNA genes, 39 pseudogenes, and 8272 protein-coding genes, of which 36% can be ascribed a putative function. These include genes involved in host-pathogen interactions, such as proteolytic enzymes, and extensive machinery for synthesis of complex surface glycoconjugates. The organization of protein-coding genes into long, strand-specific, polycistronic clusters and lack of general transcription factors in the L. major, Trypanosoma brucei, and Trypanosoma cruzi (Tritryp) genomes suggest that the mechanisms regulating RNA polymerase II-directed transcription are distinct from those operating in other eukaryotes, although the trypanosomatids appear capable of chromatin remodeling. Abundant RNA-binding proteins are encoded in the Tritryp genomes, consistent with active posttranscriptional regulation of gene expression."xsd:string |
| http://purl.uniprot.org/citations/16020728 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.1112680"xsd:string |
| http://purl.uniprot.org/citations/16020728 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.1112680"xsd:string |
| http://purl.uniprot.org/citations/16020728 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.1112680"xsd:string |
| http://purl.uniprot.org/citations/16020728 | http://purl.uniprot.org/core/author | "Aert R."xsd:string |
| http://purl.uniprot.org/citations/16020728 | http://purl.uniprot.org/core/author | "Aert R."xsd:string |
| http://purl.uniprot.org/citations/16020728 | http://purl.uniprot.org/core/author | "Aert R."xsd:string |
| http://purl.uniprot.org/citations/16020728 | http://purl.uniprot.org/core/author | "Adlem E."xsd:string |
| http://purl.uniprot.org/citations/16020728 | http://purl.uniprot.org/core/author | "Adlem E."xsd:string |
| http://purl.uniprot.org/citations/16020728 | http://purl.uniprot.org/core/author | "Adlem E."xsd:string |
| http://purl.uniprot.org/citations/16020728 | http://purl.uniprot.org/core/author | "Barrell B."xsd:string |
| http://purl.uniprot.org/citations/16020728 | http://purl.uniprot.org/core/author | "Barrell B.G."xsd:string |
| http://purl.uniprot.org/citations/16020728 | http://purl.uniprot.org/core/author | "Barrell B.G."xsd:string |
| http://purl.uniprot.org/citations/16020728 | http://purl.uniprot.org/core/author | "Barrell B.G."xsd:string |
| http://purl.uniprot.org/citations/16020728 | http://purl.uniprot.org/core/author | "Bason N."xsd:string |
| http://purl.uniprot.org/citations/16020728 | http://purl.uniprot.org/core/author | "Bason N."xsd:string |
| http://purl.uniprot.org/citations/16020728 | http://purl.uniprot.org/core/author | "Bason N."xsd:string |
| http://purl.uniprot.org/citations/16020728 | http://purl.uniprot.org/core/author | "Beck A."xsd:string |
| http://purl.uniprot.org/citations/16020728 | http://purl.uniprot.org/core/author | "Beck A."xsd:string |
| http://purl.uniprot.org/citations/16020728 | http://purl.uniprot.org/core/author | "Beck A."xsd:string |
| http://purl.uniprot.org/citations/16020728 | http://purl.uniprot.org/core/author | "Cronin A."xsd:string |
| http://purl.uniprot.org/citations/16020728 | http://purl.uniprot.org/core/author | "Cronin A."xsd:string |