Results

RDF/XMLNTriplesTurtleShow queryShare ▶
SubjectPredicateObject
http://purl.uniprot.org/citations/16021077http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/16021077http://www.w3.org/2000/01/rdf-schema#comment"

Objective

We measured maternal serum soluble fms-like tyrosine kinase 1 concentrations across pregnancy and immediately postpartum in women who developed preeclampsia and normal pregnant women.

Study design

This was a nested case control study of 113 normal pregnant women and 55 women with preeclampsia.

Results

Serum soluble fms-like tyrosine kinase 1 concentrations increased similarly in early pregnancy in both groups. Mean serum soluble fms-like tyrosine kinase 1 concentrations were increased in women who developed preeclampsia, compared with normal pregnant women, and this increase was most pronounced in severe preeclampsia. However, many women with preeclampsia had soluble fms-like tyrosine kinase 1 concentrations similar to normal pregnant women. Lastly, soluble fms-like tyrosine kinase 1 decreased rapidly after delivery, but this decrease was significantly slower in women with severe preeclampsia.

Conclusion

Increased soluble fms-like tyrosine kinase 1 is not an early-pregnancy event among women who later develop preeclampsia. Increased soluble fms-like tyrosine kinase 1 is more likely to be present in women with severe preeclampsia, but it is not present in all women with preeclampsia. Soluble fms-like tyrosine kinase 1 concentrations decrease more slowly after delivery in women with preeclampsia, consistent with a decreased rate of excretion or continued production."xsd:string
http://purl.uniprot.org/citations/16021077http://purl.org/dc/terms/identifier"doi:10.1016/j.ajog.2004.11.038"xsd:string
http://purl.uniprot.org/citations/16021077http://purl.uniprot.org/core/author"Roberts J.M."xsd:string
http://purl.uniprot.org/citations/16021077http://purl.uniprot.org/core/author"Cooper K.M."xsd:string
http://purl.uniprot.org/citations/16021077http://purl.uniprot.org/core/author"Frank M.P."xsd:string
http://purl.uniprot.org/citations/16021077http://purl.uniprot.org/core/author"Gallaher M.J."xsd:string
http://purl.uniprot.org/citations/16021077http://purl.uniprot.org/core/author"Powers R.W."xsd:string
http://purl.uniprot.org/citations/16021077http://purl.uniprot.org/core/author"Ness R.B."xsd:string
http://purl.uniprot.org/citations/16021077http://purl.uniprot.org/core/author"Harger G.F."xsd:string
http://purl.uniprot.org/citations/16021077http://purl.uniprot.org/core/date"2005"xsd:gYear
http://purl.uniprot.org/citations/16021077http://purl.uniprot.org/core/name"Am J Obstet Gynecol"xsd:string
http://purl.uniprot.org/citations/16021077http://purl.uniprot.org/core/pages"185-191"xsd:string
http://purl.uniprot.org/citations/16021077http://purl.uniprot.org/core/title"Maternal serum soluble fms-like tyrosine kinase 1 concentrations are not increased in early pregnancy and decrease more slowly postpartum in women who develop preeclampsia."xsd:string
http://purl.uniprot.org/citations/16021077http://purl.uniprot.org/core/volume"193"xsd:string
http://purl.uniprot.org/citations/16021077http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/16021077
http://purl.uniprot.org/citations/16021077http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/16021077
http://purl.uniprot.org/uniprot/#_H9N1E7-mappedCitation-16021077http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/16021077
http://purl.uniprot.org/uniprot/#_H9N1E8-mappedCitation-16021077http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/16021077
http://purl.uniprot.org/uniprot/#_B5A924-mappedCitation-16021077http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/16021077
http://purl.uniprot.org/uniprot/#_B1AC84-mappedCitation-16021077http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/16021077
http://purl.uniprot.org/uniprot/#_P17948-mappedCitation-16021077http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/16021077
http://purl.uniprot.org/uniprot/#_L7RSL3-mappedCitation-16021077http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/16021077
http://purl.uniprot.org/uniprot/#_Q16332-mappedCitation-16021077http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/16021077
http://purl.uniprot.org/uniprot/#_Q16333-mappedCitation-16021077http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/16021077
▶