DESCRIBE <http://purl.uniprot.org/citations/16026775>

Subject	Predicate	Object
http://purl.uniprot.org/citations/16026775	http://www.w3.org/1999/02/22-rdf-syntax-ns#type	http://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/16026775	http://www.w3.org/2000/01/rdf-schema#comment	" Background Survivin and livin are highly expressed in cancer cells and transformed cells, but show little or no expression in normal differentiated tissues. Human antibody responses to tumor-associated antigens have been detected, but little is known about the response to survivin and livin in breast cancer patients. Methods We examined the prevalence of anti-survivin and livin antibodies in breast cancer patients with a specific enzyme-linked immunosorbent assay (ELISA) using recombinant protein. Results Using a cutoff value for positivity determined as the mean absorbance +2SD for healthy control samples, sera from 11 of 46 breast cancer patients (23.9%) were positive by the ELISA using recombinant survivin protein. Of 46 samples from the same breast cancer patients, 15 (32.6%) were positive for anti-livin antibodies. In addition, 24 (52.2%) were positive for 1 or both ELISAs using the respective proteins. Intensity of anti-livin antibody responses did not correlate with intensity of anti-survivin responses. Conclusions Anti-livin antibodies were detected in sera from breast cancer patients by an anti-livin ELISA using full-length recombinant livin protein. Like survivin, livin may act as a major cancer antigen in breast cancer patients."xsd:string
http://purl.uniprot.org/citations/16026775	http://purl.org/dc/terms/identifier	"doi:10.1016/j.cccn.2005.06.009"xsd:string
http://purl.uniprot.org/citations/16026775	http://purl.uniprot.org/core/author	"Sato N."xsd:string
http://purl.uniprot.org/citations/16026775	http://purl.uniprot.org/core/author	"Watanabe N."xsd:string
http://purl.uniprot.org/citations/16026775	http://purl.uniprot.org/core/author	"Hirata K."xsd:string
http://purl.uniprot.org/citations/16026775	http://purl.uniprot.org/core/author	"Tsuji N."xsd:string
http://purl.uniprot.org/citations/16026775	http://purl.uniprot.org/core/author	"Kobayashi D."xsd:string
http://purl.uniprot.org/citations/16026775	http://purl.uniprot.org/core/author	"Torigoe T."xsd:string
http://purl.uniprot.org/citations/16026775	http://purl.uniprot.org/core/author	"Ohmura T."xsd:string
http://purl.uniprot.org/citations/16026775	http://purl.uniprot.org/core/author	"Asanuma K."xsd:string
http://purl.uniprot.org/citations/16026775	http://purl.uniprot.org/core/author	"Yagihashi A."xsd:string
http://purl.uniprot.org/citations/16026775	http://purl.uniprot.org/core/date	"2005"xsd:gYear
http://purl.uniprot.org/citations/16026775	http://purl.uniprot.org/core/name	"Clin Chim Acta"xsd:string
http://purl.uniprot.org/citations/16026775	http://purl.uniprot.org/core/pages	"125-130"xsd:string
http://purl.uniprot.org/citations/16026775	http://purl.uniprot.org/core/title	"Detection of autoantibodies to survivin and livin in sera from patients with breast cancer."xsd:string
http://purl.uniprot.org/citations/16026775	http://purl.uniprot.org/core/volume	"362"xsd:string
http://purl.uniprot.org/citations/16026775	http://www.w3.org/2004/02/skos/core#exactMatch	http://purl.uniprot.org/pubmed/16026775
http://purl.uniprot.org/citations/16026775	http://xmlns.com/foaf/0.1/primaryTopicOf	https://pubmed.ncbi.nlm.nih.gov/16026775
http://purl.uniprot.org/uniprot/#_A0A0B4J1S3-mappedCitation-16026775	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/16026775
http://purl.uniprot.org/uniprot/#_A0A7L8XZM3-mappedCitation-16026775	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/16026775
http://purl.uniprot.org/uniprot/#_A3E0Z5-mappedCitation-16026775	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/16026775
http://purl.uniprot.org/uniprot/#_A3E0Z6-mappedCitation-16026775	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/16026775
http://purl.uniprot.org/uniprot/#_A3E0Z7-mappedCitation-16026775	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/16026775
http://purl.uniprot.org/uniprot/#_A3E0Z8-mappedCitation-16026775	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/16026775