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http://purl.uniprot.org/citations/16053028http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/16053028http://www.w3.org/2000/01/rdf-schema#comment"

Background and aim

Sarcoidosis has been reported to be associated with the HLA genes, in particular DQB1.

Methods

High resolution DQB 1 of 103 sarcoidosis patients was obtained by sequence-based typing; low resolution HLA-A/B/DRB 1 typing was performed by serological and molecular methods. Small fiber neuropathy (SFN) was established by thermal threshold testing.

Results

Sixty-seven patients suffered from SFN (SFN+), in 36 patients SFN was absent (SFN-). Comparing HLA DQB 1 typings of SFN+ patients, SFN-patients and control individuals revealed a significant increase of the allele DQB 1 0602 in SFN+ patients compared to controls.

Conclusion

This association might be correlated with a severe course of the disease."xsd:string
http://purl.uniprot.org/citations/16053028http://purl.org/dc/terms/identifier"doi:10.1007/s11083-005-9013-x"xsd:string
http://purl.uniprot.org/citations/16053028http://purl.uniprot.org/core/author"Voorter C.E."xsd:string
http://purl.uniprot.org/citations/16053028http://purl.uniprot.org/core/author"van den Berg-Loonen E.M."xsd:string
http://purl.uniprot.org/citations/16053028http://purl.uniprot.org/core/author"Drent M."xsd:string
http://purl.uniprot.org/citations/16053028http://purl.uniprot.org/core/author"Faber K.G."xsd:string
http://purl.uniprot.org/citations/16053028http://purl.uniprot.org/core/author"Hoitsma E."xsd:string
http://purl.uniprot.org/citations/16053028http://purl.uniprot.org/core/date"2005"xsd:gYear
http://purl.uniprot.org/citations/16053028http://purl.uniprot.org/core/name"Sarcoidosis Vasc Diffuse Lung Dis"xsd:string
http://purl.uniprot.org/citations/16053028http://purl.uniprot.org/core/pages"129-132"xsd:string
http://purl.uniprot.org/citations/16053028http://purl.uniprot.org/core/title"Association of HLA DQB1 0602 in sarcoidosis patients with small fiber neuropathy."xsd:string
http://purl.uniprot.org/citations/16053028http://purl.uniprot.org/core/volume"22"xsd:string
http://purl.uniprot.org/citations/16053028http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/16053028
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http://purl.uniprot.org/uniprot/#_A0A0E3DC97-mappedCitation-16053028http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/16053028
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