http://purl.uniprot.org/citations/16055554 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/16055554 | http://www.w3.org/2000/01/rdf-schema#comment | "B cell homeostasis is maintained by a balance between the continual generation of new cells and their elimination. Here we show proapoptotic BCL-2 family members BAX and BAK are essential for regulating the number of B cells at both immature and mature developmental stages. BAX and BAK are critical mediators of B cell death induced by multiple stimuli. In addition, BAX- and BAK-deficient B cells display defective cell cycle progression to B cell receptor crosslinking and lipopolysaccharide, but not to CpG-DNA. Furthermore, inducible deletion of Bax and Bak in adult mice results in the development of severe autoimmune disease."xsd:string |
http://purl.uniprot.org/citations/16055554 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.0504783102"xsd:string |
http://purl.uniprot.org/citations/16055554 | http://purl.uniprot.org/core/author | "Harada H."xsd:string |
http://purl.uniprot.org/citations/16055554 | http://purl.uniprot.org/core/author | "Takeuchi O."xsd:string |
http://purl.uniprot.org/citations/16055554 | http://purl.uniprot.org/core/author | "Suh H."xsd:string |
http://purl.uniprot.org/citations/16055554 | http://purl.uniprot.org/core/author | "Korsmeyer S.J."xsd:string |
http://purl.uniprot.org/citations/16055554 | http://purl.uniprot.org/core/author | "Fisher J."xsd:string |
http://purl.uniprot.org/citations/16055554 | http://purl.uniprot.org/core/author | "Malynn B.A."xsd:string |
http://purl.uniprot.org/citations/16055554 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
http://purl.uniprot.org/citations/16055554 | http://purl.uniprot.org/core/name | "Proc Natl Acad Sci U S A"xsd:string |
http://purl.uniprot.org/citations/16055554 | http://purl.uniprot.org/core/pages | "11272-11277"xsd:string |
http://purl.uniprot.org/citations/16055554 | http://purl.uniprot.org/core/title | "Essential role of BAX,BAK in B cell homeostasis and prevention of autoimmune disease."xsd:string |
http://purl.uniprot.org/citations/16055554 | http://purl.uniprot.org/core/volume | "102"xsd:string |
http://purl.uniprot.org/citations/16055554 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/16055554 |
http://purl.uniprot.org/citations/16055554 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/16055554 |
http://purl.uniprot.org/uniprot/O08734#attribution-46720B48708DA952A49CE96F203AE0DF | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/16055554 |
http://purl.uniprot.org/uniprot/O08734#attribution-E15B0CDA31EB8D84F1BEAE0944B4AE37 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/16055554 |
http://purl.uniprot.org/uniprot/O54918#attribution-46720B48708DA952A49CE96F203AE0DF | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/16055554 |
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http://purl.uniprot.org/uniprot/Q07813#attribution-E15B0CDA31EB8D84F1BEAE0944B4AE37 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/16055554 |
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http://purl.uniprot.org/uniprot/#_Q07813-mappedCitation-16055554 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16055554 |
http://purl.uniprot.org/uniprot/#_A0A1B0GT35-mappedCitation-16055554 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16055554 |
http://purl.uniprot.org/uniprot/#_A0A1B0GT81-mappedCitation-16055554 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16055554 |