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http://purl.uniprot.org/citations/16077004http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/16077004http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/16077004http://www.w3.org/2000/01/rdf-schema#comment"beta-Catenin regulates cell adhesion and cellular differentiation during development, and misregulation of beta-catenin contributes to numerous forms of cancer in humans. Here we describe Caenorhabditis elegans conditional alleles of mom-2/Wnt, mom-4/Tak1, and wrm-1/beta-catenin. We use these reagents to examine the regulation of WRM-1/beta-catenin during a Wnt-signaling-induced asymmetric cell division. While WRM-1 protein initially accumulates in the nuclei of all cells, signaling promotes the retention of WRM-1 in nuclei of responding cells. We show that both PRY-1/Axin and the nuclear exportin homolog IMB-4/CRM-1 antagonize signaling. These findings reveal how Wnt signals direct the asymmetric localization of beta-catenin during polarized cell division."xsd:string
http://purl.uniprot.org/citations/16077004http://purl.org/dc/terms/identifier"doi:10.1101/gad.1323705"xsd:string
http://purl.uniprot.org/citations/16077004http://purl.org/dc/terms/identifier"doi:10.1101/gad.1323705"xsd:string
http://purl.uniprot.org/citations/16077004http://purl.uniprot.org/core/author"Kim S."xsd:string
http://purl.uniprot.org/citations/16077004http://purl.uniprot.org/core/author"Kim S."xsd:string
http://purl.uniprot.org/citations/16077004http://purl.uniprot.org/core/author"Nakamura K."xsd:string
http://purl.uniprot.org/citations/16077004http://purl.uniprot.org/core/author"Nakamura K."xsd:string
http://purl.uniprot.org/citations/16077004http://purl.uniprot.org/core/author"Trzepacz C."xsd:string
http://purl.uniprot.org/citations/16077004http://purl.uniprot.org/core/author"Trzepacz C."xsd:string
http://purl.uniprot.org/citations/16077004http://purl.uniprot.org/core/author"Ishidate T."xsd:string
http://purl.uniprot.org/citations/16077004http://purl.uniprot.org/core/author"Ishidate T."xsd:string
http://purl.uniprot.org/citations/16077004http://purl.uniprot.org/core/author"Bei Y."xsd:string
http://purl.uniprot.org/citations/16077004http://purl.uniprot.org/core/author"Bei Y."xsd:string
http://purl.uniprot.org/citations/16077004http://purl.uniprot.org/core/author"Mello C.C."xsd:string
http://purl.uniprot.org/citations/16077004http://purl.uniprot.org/core/author"Mello C.C."xsd:string
http://purl.uniprot.org/citations/16077004http://purl.uniprot.org/core/author"Shirayama M."xsd:string
http://purl.uniprot.org/citations/16077004http://purl.uniprot.org/core/author"Shirayama M."xsd:string
http://purl.uniprot.org/citations/16077004http://purl.uniprot.org/core/author"Pang K."xsd:string
http://purl.uniprot.org/citations/16077004http://purl.uniprot.org/core/author"Pang K."xsd:string
http://purl.uniprot.org/citations/16077004http://purl.uniprot.org/core/author"Brownell D.R."xsd:string
http://purl.uniprot.org/citations/16077004http://purl.uniprot.org/core/author"Brownell D.R."xsd:string
http://purl.uniprot.org/citations/16077004http://purl.uniprot.org/core/date"2005"xsd:gYear
http://purl.uniprot.org/citations/16077004http://purl.uniprot.org/core/date"2005"xsd:gYear