| http://purl.uniprot.org/citations/16103458 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16103458 | http://www.w3.org/2000/01/rdf-schema#comment | "Associations of genetic factors with malignant gliomas have been modest. We examined the relationships of human leukocyte antigen (HLA) and related polymorphisms to glioblastoma multiforme in adult Caucasians (non-Hispanic Whites) from the San Francisco Bay area. For 155 glioblastoma multiforme patients and 157 control subjects closely matched by ethnicity, age, and gender, PCR-based techniques resolved alleles at HLA-A, -B, -C, and -DRB1 loci along with short tandem repeat polymorphisms of MICA exon 5 and TNFb. By multivariable logistic regression, B*13 and the B*07-Cw*07 haplotype were positively associated with glioblastoma multiforme (P=0.01 and <0.001, respectively), whereas Cw*01 was the only variant showing a negative association (P=0.05). Among glioblastoma multiforme patients, progression to death after diagnosis was slower in those with A*32 (relative hazard, 0.45; P<0.01) and faster in those with B*55 (relative hazard, 2.27; P<0.01). Thus, both the occurrence and the prognosis of glioblastoma multiforme could be associated with specific but different HLA genotypes. B*07 and the B*07-Cw*07 haplotype are much more common in Caucasians than other ethnic groups in the U.S., which may partially explain the higher incidence of glioblastoma multiforme in Caucasians."xsd:string |
| http://purl.uniprot.org/citations/16103458 | http://purl.org/dc/terms/identifier | "doi:10.1158/1055-9965.epi-05-0136"xsd:string |
| http://purl.uniprot.org/citations/16103458 | http://purl.uniprot.org/core/author | "Li Y."xsd:string |
| http://purl.uniprot.org/citations/16103458 | http://purl.uniprot.org/core/author | "Tang J."xsd:string |
| http://purl.uniprot.org/citations/16103458 | http://purl.uniprot.org/core/author | "Cobbs C.S."xsd:string |
| http://purl.uniprot.org/citations/16103458 | http://purl.uniprot.org/core/author | "Shao W."xsd:string |
| http://purl.uniprot.org/citations/16103458 | http://purl.uniprot.org/core/author | "Kaslow R.A."xsd:string |
| http://purl.uniprot.org/citations/16103458 | http://purl.uniprot.org/core/author | "Miike R."xsd:string |
| http://purl.uniprot.org/citations/16103458 | http://purl.uniprot.org/core/author | "Wiencke J.K."xsd:string |
| http://purl.uniprot.org/citations/16103458 | http://purl.uniprot.org/core/author | "Wrensch M."xsd:string |
| http://purl.uniprot.org/citations/16103458 | http://purl.uniprot.org/core/author | "Dorak M.T."xsd:string |
| http://purl.uniprot.org/citations/16103458 | http://purl.uniprot.org/core/author | "Lobashevsky E."xsd:string |
| http://purl.uniprot.org/citations/16103458 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
| http://purl.uniprot.org/citations/16103458 | http://purl.uniprot.org/core/name | "Cancer Epidemiol Biomarkers Prev"xsd:string |
| http://purl.uniprot.org/citations/16103458 | http://purl.uniprot.org/core/pages | "2040-2044"xsd:string |
| http://purl.uniprot.org/citations/16103458 | http://purl.uniprot.org/core/title | "Positive and negative associations of human leukocyte antigen variants with the onset and prognosis of adult glioblastoma multiforme."xsd:string |
| http://purl.uniprot.org/citations/16103458 | http://purl.uniprot.org/core/volume | "14"xsd:string |
| http://purl.uniprot.org/citations/16103458 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/16103458 |
| http://purl.uniprot.org/citations/16103458 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/16103458 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C3H3-mappedCitation-16103458 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16103458 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C3I1-mappedCitation-16103458 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16103458 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C3I5-mappedCitation-16103458 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16103458 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C548-mappedCitation-16103458 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16103458 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C549-mappedCitation-16103458 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16103458 |